Product Name :
Caveolin-1 Mouse monoclonal antibody Background :
Caveolin, an integral membrane protein, is a principal component of caveolae membranes in vivo. Two isoforms of caveolin have been identified: a slower migrating 24-kDa species ( -isoform) and a faster migrating 21-kDa species ( -isoform). Caveolins interact with multiple signaling molecules, such as the G-protein alpha subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases and eNOS. Caveolin-1 has been implicated in the pathogenesis of mammary epithelial cell hyperplasia. Product :
Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This antibody detects endogenous levels of Caveolin-1 and does not cross-react with related proteins. Immunogen :
This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to caveolin-1. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of Caveolin-1 Mouse mAb at 1:500 dilution Lane1:F9 whole cell lysate Lane2:A549 whole cell lysate Lane3:The lung tissue lysate of Mouse Lane4:The liver tissue lysate of Mouse Lane5:The lung tissue lysate of Human Lane6:Hela whole cell lysate Lane7:HepG2 whole cell lysate Lane8:Jurkat whole cell lysate
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  Immunohistochemical analysis of paraffin-embedded rat lung tissue using anti-Caveolin-1antibody. Counter stained with hematoxylin.
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  Immunohistochemical analysis of paraffin-embedded rat lung tissue using anti-Caveolin-1antibody. Counter stained with hematoxylin.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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