RRP7A/RRP7B polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
RRP7A/RRP7B polyclonal antibody Background :
RRP7A (ribosomal RNA processing 7 homolog A), also known as CGI-96 or gastric cancer antigen Zg14, is a 280 amino acid protein that contains one RRM domain. RRP7A is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
RRP7A/RRP7B polyclonal antibody detects endogenous levels of RRP7A/RRP7B protein. Immunogen :
Synthetic peptide, corresponding to amino acids 230-280 of Human RRP7A. Conjugate :
Unconjugated Modification :
Unmodification
RRP7A/RRP7B polyclonal antibody Background :
RRP7A (ribosomal RNA processing 7 homolog A), also known as CGI-96 or gastric cancer antigen Zg14, is a 280 amino acid protein that contains one RRM domain. RRP7A is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
RRP7A/RRP7B polyclonal antibody detects endogenous levels of RRP7A/RRP7B protein. Immunogen :
Synthetic peptide, corresponding to amino acids 230-280 of Human RRP7A. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of RRP7A/RRP7B polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug) Lane5:MCF-7 whole cell lysate(40ug)
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.