Product Name :
COL19A1 (Y442) polyclonal antibody Background :
Collagen Type XIX is an 1,142 amino acid protein encoded by the human gene COL19A1. Collagen Type XIX belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Collagen Type XIX is thought to act as a cross-bridge between collagen fibrils and other extracellular matrix molecules. Collagen Type XIX is also believed to be involved in skeletal myogenesis in the developing esophagus. It may also play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Collagen Type XIX is normally found as an oligomer, the subunits being disulfide-linked. Expression of Collagen Type XIX is mainly localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
COL19A1 (Y442) polyclonal antibody detects endogenous levels of COL19A1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 411-464of Human COL19A1. Conjugate :
Unconjugated Modification :
Unmodification

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  Immunohistochemistry (IHC) analyzes of COL19A1 (Y442) pAb in paraffin-embedded human breast carcinoma tissue at 1:50,showing nucleus staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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