Product Name :
Cathepsin L2 (L114) polyclonal antibody Background :
Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Cathepsin L2 (L114) polyclonal antibody detects endogenous levels of Cathepsin L2 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 91-140 of Human Cathepsin L2. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of Cathepsin L2 (L114) pAb at 1:1000 dilution Lane1:The Testis tissue lysate of Mouse(40ug) Lane2:The Testis tissue lysate of Rat(40ug) Lane3:L02 whole cell lysate(20ug) Lane4:A375 whole cell lysate(20ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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