Product Name :
ARL2BP polyclonal antibody Background :
ADP-ribosylation factors (ARFs) are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL2 (ADP-ribosylation factor-like protein 2) functions as a component of a secretory pathway that is involved in the calcium-dependent release of acetylcholine. Additionally, ARL2 plays a role in the folding of tubule proteins, thereby playing an important role in microtubule dynamics and cell cycle progression. BART1 (Binder of ARL2 protein 1), also known as ARL2BP (ADP-ribosylation factor-like protein 2-binding protein), is a 163 amino acid protein that interacts with GTP-bound ARL2 complexes and therefore may play a role in modulating ARL2 activity. Though predominantly cytosolic, BART1 can enter the mitochondria and bind the adenine nucleotide transporter when bound to ARL2. There are two isoforms of BART1 that are produced as a result of alternative splicing events. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ARL2BP polyclonal antibody detects endogenous levels of ARL2BP protein. Immunogen :
Synthetic peptide, corresponding to amino acids 104-148 of Human ARL2BP. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of ARL2BP polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate(20ug) Lane2:HEK293T whole cell lysate(20ug) Lane3:PC12 whole cell lysate(40ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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