TAGAP polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
TAGAP polyclonal antibody Background :
TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP mayfunction as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases andmapsto human chromosome 6q25.3. Making up nearly 6% of the human genome,chromosome 6 contains around 1,200 geneswithin 170million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is as sociatedwith early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is as sociated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson’s disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency andmaple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
TAGAP polyclonal antibody detects endogenous levels of TAGAP protein. Immunogen :
Synthetic peptide, corresponding to amino acids 186-231 of Human TAGAP. Conjugate :
Unconjugated Modification :
Unmodification
TAGAP polyclonal antibody Background :
TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP mayfunction as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases andmapsto human chromosome 6q25.3. Making up nearly 6% of the human genome,chromosome 6 contains around 1,200 geneswithin 170million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is as sociatedwith early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is as sociated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson’s disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency andmaple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
TAGAP polyclonal antibody detects endogenous levels of TAGAP protein. Immunogen :
Synthetic peptide, corresponding to amino acids 186-231 of Human TAGAP. Conjugate :
Unconjugated Modification :
Unmodification
-
Western blot (WB) analysis of TAGAP polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:RAW264.7 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug) Lane5:H9C2 whole cell lysate(40ug)
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.