Product Name :
CDH20 polyclonal antibody Background :
The cadherins are a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. CDH20 (cadherin 20, type 2), also known as Cdh7 or CDH7L3, is an 801 amino acid single-pass type I membrane protein that contains five cadherin domains and belongs to the cadherin superfamily. Expressed in both adult and fetal brain, as well as in placenta, CDH20 functions as a calcium-dependent cell adhesion protein that is thought to participate in the sorting of heterogeneous cell types. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CDH20 polyclonal antibody detects endogenous levels of CDH20 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 97-142 of Human CDH20. Conjugate :
Unconjugated Modification :
Unmodification
CDH20 polyclonal antibody Background :
The cadherins are a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. CDH20 (cadherin 20, type 2), also known as Cdh7 or CDH7L3, is an 801 amino acid single-pass type I membrane protein that contains five cadherin domains and belongs to the cadherin superfamily. Expressed in both adult and fetal brain, as well as in placenta, CDH20 functions as a calcium-dependent cell adhesion protein that is thought to participate in the sorting of heterogeneous cell types. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CDH20 polyclonal antibody detects endogenous levels of CDH20 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 97-142 of Human CDH20. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of CDH20 polyclonal antibody at 1:500 dillution Lane1:Hela whole cell lysate(40μg) Lane2:The Liver tissue lysate of Rat(40μg) Lane3:The Liver tissue lysate of Mouse (40μg)
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.