Product Name :
TSHZ2 polyclonal antibody Background :
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. TSHZ2 (Teashirt homolog 2), also known as ZNF218 (Zinc finger protein 218) and OVC10-2 (Ovarian cancer-related protein 10-2), is a 1034 amino acid nuclear protein that contains one homeobox DNA-binding domain, as well as five C2H2-type zinc fingers. In drosophilia, teashirt genes function as region-specific homeotic genes that specify trunk identity during embryogenesis and these genes seem to conserve the same function in mice. The gene encoding TSHZ2 maps to human chromosome 20, which comprises approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
TSHZ2 polyclonal antibody detects endogenous levels of TSHZ2 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 818-863 of Human TSHZ2. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of TSHZ2 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:The Heart tissue lysate of Rat(30ug) Lane3:The Heart tissue lysate of Mouse(30ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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