Product Name :
RAB41 polyclonal antibody Background :
Rab 41 (Ras-related protein Rab-41) is a 222 amino acid protein that belongs to the small GTPase superfamily and the Rab family.Members of the Rab familyfunction asregulators ofmembrane trafficking. Theycycle between inactive GDP-bound and activated GTP-bound states,which iscontrolled by GTP hydrolysis-activating proteins(GAPs). Rab 41 can be activated bythe GAP protein RN-Tre.Localizing to the Golgicomplex, Rab 41 isinvolved in protein transport and participatesin GTP binding. Existing astwo alternativelyspliced isoforms, the gene that encodesthe Rab 41 proteinmapsto human chromosome Xq13.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchennemuscular dystrophy arewellknown X chromosome-linked conditionswhich affectmales more frequently asmalescarry a single X chromosome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
RAB41 polyclonal antibody detects endogenous levels of RAB41 protein. Immunogen :
A synthetic peptide corresponding to residues in Human RAB41. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of RAB41 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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