Product Name :
ATXN7L1 polyclonal antibody Background :
ATXN7L1 (ataxin-7-like protein 1) is an 833 animo acid protein thatcontains one SCA7 domain. The ATXN7L1 gene isconserved in chimpanzee,canine, mouse, rat and chicken, andmapsto human chromosome 7q22.3. Chromosome 7 is about 158 milllion baseslong, encodes over 1,000 genes and makes up about 5%of the human genome. Chromosome 7 has been linked to osteogenes is imperfecta, Pendred syndrome, lissencephaly,citrullinemia and Shwachman Diamond syndrome. The deletion of a portion of the q armofchromosome 7 is associatedwith Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusualcomfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q armofchromosome 7 are also seen in a number ofmyeloid disordersincluding cases of acutemyelo Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ATXN7L1 polyclonal antibody detects endogenous levels of ATXN7L1 protein. Immunogen :
A synthetic peptide corresponding to residues in Human ATXN7L1. Conjugate :
Unconjugated Modification :
Unmodification
ATXN7L1 polyclonal antibody Background :
ATXN7L1 (ataxin-7-like protein 1) is an 833 animo acid protein thatcontains one SCA7 domain. The ATXN7L1 gene isconserved in chimpanzee,canine, mouse, rat and chicken, andmapsto human chromosome 7q22.3. Chromosome 7 is about 158 milllion baseslong, encodes over 1,000 genes and makes up about 5%of the human genome. Chromosome 7 has been linked to osteogenes is imperfecta, Pendred syndrome, lissencephaly,citrullinemia and Shwachman Diamond syndrome. The deletion of a portion of the q armofchromosome 7 is associatedwith Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusualcomfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q armofchromosome 7 are also seen in a number ofmyeloid disordersincluding cases of acutemyelo Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ATXN7L1 polyclonal antibody detects endogenous levels of ATXN7L1 protein. Immunogen :
A synthetic peptide corresponding to residues in Human ATXN7L1. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of ATXN7L1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate Lane4:HELA whole cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.