Product Name :
TGIF2LY polyclonal antibody Background :
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species. It also functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and control of gene expression. TGIF2LY (TGFB-induced factor homeobox 2-like, Y-linked), also known as TGIFLY, is a 185 amino acid testis-specific nuclear protein that functions as a transcriptional regulator during spermatid maturation. TGIF2LY belongs to the TALE/TGIF homeobox family and contains one homeobox DNA-binding domain. The gene encoding TGIF2LY maps within a male specific region of chromosome Y, in a region implied to form following a large X-to-Y transposition. The C-terminal region of TGIF2LY differs from the C-terminal region of its chromosome X homolog TGIF2LX, which suggests that TGIF2LY may act as a competitor or regulator of TGIF2LX. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
TGIF2LY polyclonal antibody detects endogenous levels of TGIF2LY protein. Immunogen :
A synthetic peptide corresponding to residues in Human TGIF2LY Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of TGIF2LY polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Jurkat whole cell lysate Lane3:PC12 whole cell lysate

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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