ETAA1 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
ETAA1 polyclonal antibody Background :
ETAA1 (Ewing's tumor-associated antigen 1), also known as ETAA16, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA1 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alström syndrome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ETAA1 polyclonal antibody detects endogenous levels of ETAA1 protein. Immunogen :
A synthetic peptide corresponding to residues in Human ETAA1. Conjugate :
Unconjugated Modification :
Unmodification
ETAA1 polyclonal antibody Background :
ETAA1 (Ewing's tumor-associated antigen 1), also known as ETAA16, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA1 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA1 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alström syndrome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ETAA1 polyclonal antibody detects endogenous levels of ETAA1 protein. Immunogen :
A synthetic peptide corresponding to residues in Human ETAA1. Conjugate :
Unconjugated Modification :
Unmodification
-
Western blot (WB) analysis of ETAA1 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:PC12 whole cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.