CIB4 polyclonal antibody 
Datasheet
COA
MSDS
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Product Name :
CIB4 polyclonal antibody Background :
CIB4 (calciumand integrin-binding familymember 4) is a 185 amino acid protein thatcontainsthree EF-hand domains. CIB4 is closelyrelated to CIB (CIB has one less EF-hand domain),which isknown to bind to IntegrinαIIβ in platelets and isinvolved in signal transduction. The gene encoding CIB4mapsto human chromosome 2,which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare andmorbid skin deformity, is associatedwithmutationsin the ABCA12 gene,while the lipidmetabolic disordersitosterolemia is associated with defectsin the ABCG5 and ABCG8 genes. Additionally, an extremelyrare recessive genetic disorder, Alströmsyndrome, iscaused bymutationsin the ALMS1 gene,whichmaps to chromosome 2. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CIB4 polyclonal antibody detects endogenous levels of CIB4 protein. Immunogen :
A synthetic peptide corresponding to residues in Human CIB4. Conjugate :
Unconjugated Modification :
Unmodification
CIB4 polyclonal antibody Background :
CIB4 (calciumand integrin-binding familymember 4) is a 185 amino acid protein thatcontainsthree EF-hand domains. CIB4 is closelyrelated to CIB (CIB has one less EF-hand domain),which isknown to bind to IntegrinαIIβ in platelets and isinvolved in signal transduction. The gene encoding CIB4mapsto human chromosome 2,which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare andmorbid skin deformity, is associatedwithmutationsin the ABCA12 gene,while the lipidmetabolic disordersitosterolemia is associated with defectsin the ABCG5 and ABCG8 genes. Additionally, an extremelyrare recessive genetic disorder, Alströmsyndrome, iscaused bymutationsin the ALMS1 gene,whichmaps to chromosome 2. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CIB4 polyclonal antibody detects endogenous levels of CIB4 protein. Immunogen :
A synthetic peptide corresponding to residues in Human CIB4. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of CIB4 polyclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat liver tissue lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.