SLC39A7 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
SLC39A7 polyclonal antibody Background :
Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. ZIP7, also known as SLC39A7 (solute carrier family 39 (zinc transporter), member 7), KE4, HKE4, RING5 or H2-KE4, is a 469 amino acid multi-pass membrane protein that belongs to the ZIP transporter family. Expressed at high levels in kidney, placenta, pancreas and lung, ZIP7 functions as a zinc transporter that facilitates the movement of zinc, both from the extracellular environment and from intracellular storage compartments, to the cytosol. The gene encoding ZIP7 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SLC39A7 polyclonal antibody detects endogenous levels of SLC39A7 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 179-224 of Human SLC39A7. Conjugate :
Unconjugated Modification :
Unmodification
SLC39A7 polyclonal antibody Background :
Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. ZIP7, also known as SLC39A7 (solute carrier family 39 (zinc transporter), member 7), KE4, HKE4, RING5 or H2-KE4, is a 469 amino acid multi-pass membrane protein that belongs to the ZIP transporter family. Expressed at high levels in kidney, placenta, pancreas and lung, ZIP7 functions as a zinc transporter that facilitates the movement of zinc, both from the extracellular environment and from intracellular storage compartments, to the cytosol. The gene encoding ZIP7 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SLC39A7 polyclonal antibody detects endogenous levels of SLC39A7 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 179-224 of Human SLC39A7. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of SLC39A7 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.