ZNF187 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
ZNF187 polyclonal antibody Background :
The best studied of the immediate early genes is the c-Fos proto-oncogene. Many of the signals inducing Fos expression act through a sequence located in the 5' flanking region of c-Fos, designated the serum response element (SRE). The SRE is required for response to activators of protein kinase C and Fos growth-induced signals independent of protein kinase C. Accumulating evidence argues that the SRE is a multifunctional element that may involve the action of multiple SRE-binding proteins. These include the serum response factor (SRF) and the two less well characterized proteins, TCF p62 and BBF p62. An SRE binding nuclear protein, designated SRE-ZBP, is a member of the C2H2 zinc finger family of proteins. Like c-Fos, SRE-ZBP is serum-inducible in HeLa cells, although with slower kinetics. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ZNF187 polyclonal antibody detects endogenous levels of ZNF187 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 149-194 of Human ZNF187. Conjugate :
Unconjugated Modification :
Unmodification
ZNF187 polyclonal antibody Background :
The best studied of the immediate early genes is the c-Fos proto-oncogene. Many of the signals inducing Fos expression act through a sequence located in the 5' flanking region of c-Fos, designated the serum response element (SRE). The SRE is required for response to activators of protein kinase C and Fos growth-induced signals independent of protein kinase C. Accumulating evidence argues that the SRE is a multifunctional element that may involve the action of multiple SRE-binding proteins. These include the serum response factor (SRF) and the two less well characterized proteins, TCF p62 and BBF p62. An SRE binding nuclear protein, designated SRE-ZBP, is a member of the C2H2 zinc finger family of proteins. Like c-Fos, SRE-ZBP is serum-inducible in HeLa cells, although with slower kinetics. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ZNF187 polyclonal antibody detects endogenous levels of ZNF187 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 149-194 of Human ZNF187. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of ZNF187 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:Hela cell lysate Lane3:sp2/0 cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.