Product Name :
SRSF11 polyclonal antibody Background :
Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20 and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and a SR-rich domain. The SR factor family is not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. SFRS11 (splicing factor, arginine/serine-rich 11), also known as arginine-rich 54 kDa nuclear protein (p54) or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and belongs to the splicing factor SR family. SFRS11 may function in pre-mRNA splicing and contains one RRM (RNA recognition motif) domain. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SRSF11 polyclonal antibody detects endogenous levels of SRSF11 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 260-305 of Human SRSF11. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of SRSF11 Antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:SGC7901 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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