Product Name :
SLC39A9 polyclonal antibody Background :
ZIP9 (Zinc transporter ZIP9, Solute carrier family 39 member 9) is a multi-pass (seven transmembrane regions) membrane protein that belongs to the ZIP transporter (TC 2.A.5) family. Zinc transporters all have transmembrane domains, and are encoded by two SLC (solute-linked carrier) gene families: ZnT (SLC30) and Zip (SLC39). There are at least 9 ZnT and 15 Zip transporters in human cells. Zip transporters are believed to increase intracellular zinc by promoting zinc uptake. This may be facilitated by vesicles within the cell that release release into the cytoplasm. Zip and ZnT transporter families exhibit tissue-specific expression and respond differently to zinc deficiency and excess. ZIP9 has been shown to localize to the trans-Golgi network regardless of zinc presence. ZIP9 is believed to function as a zinc homeostasis regulator acting in the secretory pathway. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SLC39A9 polyclonal antibody detects endogenous levels of SLC39A9 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 150-195 of Human SLC39A9. Conjugate :
Unconjugated Modification :
Unmodification
SLC39A9 polyclonal antibody Background :
ZIP9 (Zinc transporter ZIP9, Solute carrier family 39 member 9) is a multi-pass (seven transmembrane regions) membrane protein that belongs to the ZIP transporter (TC 2.A.5) family. Zinc transporters all have transmembrane domains, and are encoded by two SLC (solute-linked carrier) gene families: ZnT (SLC30) and Zip (SLC39). There are at least 9 ZnT and 15 Zip transporters in human cells. Zip transporters are believed to increase intracellular zinc by promoting zinc uptake. This may be facilitated by vesicles within the cell that release release into the cytoplasm. Zip and ZnT transporter families exhibit tissue-specific expression and respond differently to zinc deficiency and excess. ZIP9 has been shown to localize to the trans-Golgi network regardless of zinc presence. ZIP9 is believed to function as a zinc homeostasis regulator acting in the secretory pathway. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SLC39A9 polyclonal antibody detects endogenous levels of SLC39A9 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 150-195 of Human SLC39A9. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of SLC39A9 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:H9C2 cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.