PSD-93 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
PSD-93 polyclonal antibody Background :
The postsynaptic density protein (PSD)-93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93. Conjugate :
Unconjugated Modification :
Unmodification
PSD-93 polyclonal antibody Background :
The postsynaptic density protein (PSD)-93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of PSD-93 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:PC12 cell lysate
Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model
PMCID: Pubmed No.:26456198
Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model
PMCID: Pubmed No.:26456198
Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model
PMCID: Pubmed No.:26456198
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.