CD32-C polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
CD32-C polyclonal antibody Background :
CD32 (also designated Fc γ RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C. These isoforms are designated CD32-A, CD32-B1, CD32-B3, and CD32-C. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the CD32-B forms are present on B lymphocytes, and the CD32-A and CD32-C forms are found on neutrophils. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CD32-C polyclonal antibody detects endogenous levels of CD32-C protein. Immunogen :
Synthetic peptide, corresponding to amino acids 278-323 of Human CD32-C. Conjugate :
Unconjugated Modification :
Unmodification
CD32-C polyclonal antibody Background :
CD32 (also designated Fc γ RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C. These isoforms are designated CD32-A, CD32-B1, CD32-B3, and CD32-C. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the CD32-B forms are present on B lymphocytes, and the CD32-A and CD32-C forms are found on neutrophils. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CD32-C polyclonal antibody detects endogenous levels of CD32-C protein. Immunogen :
Synthetic peptide, corresponding to amino acids 278-323 of Human CD32-C. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of CD32-C polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.