PHO1 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
PHO1 polyclonal antibody Background :
APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A), also known as PHO1 or ARP3 or PHRBN is a 199 amino acid protein that belongs to the cytidine deaminase family. Expressed in keratinocytes, as well as in peripherical leukocytes, APOBEC3A may be implicated in cell growth and cell cycle control. The gene encoding APOBEC3A is one of seven related genes which map to a cluster on chromosome 22 and are thought to play a role in tumor transformation and metastasis, as well as in host-associated antiviral activity. Chromosome 22 houses over 500 genes, some of which are involved in Phelan-McDermid syndrome, schizophrenia and Neurofibromatosis type 2. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PHO1 polyclonal antibody detects endogenous levels of PHO1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 67-112 of Human PHO1. Conjugate :
Unconjugated Modification :
Unmodification
PHO1 polyclonal antibody Background :
APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A), also known as PHO1 or ARP3 or PHRBN is a 199 amino acid protein that belongs to the cytidine deaminase family. Expressed in keratinocytes, as well as in peripherical leukocytes, APOBEC3A may be implicated in cell growth and cell cycle control. The gene encoding APOBEC3A is one of seven related genes which map to a cluster on chromosome 22 and are thought to play a role in tumor transformation and metastasis, as well as in host-associated antiviral activity. Chromosome 22 houses over 500 genes, some of which are involved in Phelan-McDermid syndrome, schizophrenia and Neurofibromatosis type 2. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PHO1 polyclonal antibody detects endogenous levels of PHO1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 67-112 of Human PHO1. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of PHO1 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.