Product Name :
Casein Kinase IIβ (phospho-S209) polyclonal antibody Background :
CK2 (formerly called Casein Kinase II) is a highly conserved protein kinase with more than 300 substrates regulating cell growth, cell death, and cell survival. CK2 has been implicated in the response to UV irradiation-induced DNA damage, targeting XRCC1 and BRCA1 as well as regulating p53 tumor suppressor protein functions.Furthermore, CK2 plays a key role in NF-κB activation. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -21°C long term. Avoid freeze-thaw cycles. Specificity :
Casein Kinase IIβ (phospho-S209) polyclonal antibody detects endogenous levels of Casein Kinase IIβ protein only when phosphorylated at Ser209. Immunogen :
Synthetic phosphopeptide derived from human Cytokeratin 8 around the phosphorylation site of Serine 432 Conjugate :
Unconjugated Modification :
Phosphorylation

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  Western blot (WB) analysis of Casein Kinase IIβ (phospho-S209) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate(40µg) Lane2:Panc1 whole cell lysate(40µg) Lane3:U-87MG whole cell lysate(40µg) Lane4:The Brain tissue lysate of Rat(40µg) Lane5:The Kidney tissue lysate of Mouse(40µg)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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