Septin 8 (I203) polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
Septin 8 (I203) polyclonal antibody Background :
Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 8 is a 508 amino acid protein that is expressed in the brain, cardiovascular regions, prostate, testis and ovary. Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1). Septin 8 may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized in cytoplasm. Septin 8, Septin 4 and Septin 5 surround α-granules, implicating these three septins as components of the septin complex in platelets and contributing to platelet biology. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Septin 8 (I203) polyclonal antibody detects endogenous levels of Septin 8 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 178-220 of Human Septin 8. Conjugate :
Unconjugated Modification :
Unmodification
Septin 8 (I203) polyclonal antibody Background :
Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 8 is a 508 amino acid protein that is expressed in the brain, cardiovascular regions, prostate, testis and ovary. Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1). Septin 8 may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized in cytoplasm. Septin 8, Septin 4 and Septin 5 surround α-granules, implicating these three septins as components of the septin complex in platelets and contributing to platelet biology. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Septin 8 (I203) polyclonal antibody detects endogenous levels of Septin 8 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 178-220 of Human Septin 8. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of Septin 8 (I203) pAb at 1:1000 dilution Lane1:The Brain tissue lysate of Mouse(10ug) Lane2:The Brain tissue lysate of Rat(10ug) Lane3:PC3 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.