Product Name :
Angptl7 (P346) polyclonal antibody Background :
Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Angptl7 (P346) polyclonal antibody detects endogenous levels of Angptl7 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 321-370 of Human Angptl7. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of Angptl7 (P346) pAb at 1:1000 dilution Lane1:H9C2 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(20ug)
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  Immunohistochemistry (IHC) analyzes of Angptl7 (P346) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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