Product Name :
PGE synthase (I79) polyclonal antibody Background :
Prostaglandin E synthase (PGE synthase), also known as PIG12 and MGST1-L1, is a member of protein super family MAPEG, which consists of membrane associated proteins involved in eicosanoid and glutathione metabolism. The expression of this membrane-associated protein can be induced by the pro-inflammatory cytokine, IL-1β. PGE synthase is expressed in seminal vesicles, deferent ducts, kidney, heart and spleen. The enzyme activity of PGE synthase in most organs is glutathione-dependent. PGE synthase may play a significant role in the progression of Alzheimer’s disease. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PGE synthase (I79) polyclonal antibody detects endogenous levels of PGE synthase protein. Immunogen :
Synthetic peptide, corresponding to amino acids 51-100 of Human PGE synthase. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of PGE synthase (I79) polyclonal antibody at 1:500 dilution Lane1:NIH-3T3 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:H9C2 whole cell lysate(40ug) Lane4:SP2/0 whole cell lysate(40ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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