NK-1R (K245) polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
NK-1R (K245) polyclonal antibody Background :
The neurokinin-1 (NK1) receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
NK-1R (K245) polyclonal antibody detects endogenous levels of NK-1R protein. Immunogen :
Synthetic peptide, corresponding to amino acids 215-260 of Human NK-1R. Conjugate :
Unconjugated Modification :
Unmodification
NK-1R (K245) polyclonal antibody Background :
The neurokinin-1 (NK1) receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
NK-1R (K245) polyclonal antibody detects endogenous levels of NK-1R protein. Immunogen :
Synthetic peptide, corresponding to amino acids 215-260 of Human NK-1R. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of NK-1R (K245) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Effect of Electroacupuncture Intervention on Expression of CGRP, SP, COX-1, and PGE2 of Dorsal Portion of the Cervical Spinal Cord in Rats with Neck-Incision Pain
PMCID: Pubmed No.:None
Temporospatial Expression of Neuropeptide Substance P in Dental Pulp Stem Cells during Odontoblastic Differentiation in Vitro and Reparative Dentinogenesis in Vivo
PMCID: Pubmed No.:36549466
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.