Gas6 (G309) polyclonal antibody 
Datasheet
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MSDS
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Product Name :
Gas6 (G309) polyclonal antibody Background :
Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Gas6 (G309) polyclonal antibody detects endogenous levels of Gas6 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 278-328 of Human Gas6. Conjugate :
Unconjugated Modification :
Unmodification
Gas6 (G309) polyclonal antibody Background :
Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Gas6 (G309) polyclonal antibody detects endogenous levels of Gas6 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 278-328 of Human Gas6. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of Gas6 (G309) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Mouse heart tissue lysate Lane3:PC12 whole cell lysate -
Immunohistochemistry (IHC) analyzes of Gas6 (G309) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.
Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6
PMCID: Pubmed No.:28154173
Growth arrest‐specific 6 modulates adiponectin expression and insulin resistance in adipose tissue
PMCID: Pubmed No.:32969596
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.