Product Name :
TNF-IP 1 (S122) polyclonal antibody Background :
TNFα-IP 1 (tumor necrosis factor, α-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family. TNFα-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. The expression of TNFα-IP 1 can be induced by IL-6 and by TNFα in the umbilical vein of endothelial cells. TNFα-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases. TNFα-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
TNF-IP 1 (S122) polyclonal antibody detects endogenous levels of TNF-IP 1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of TNF-IP 1 (S122) pAb at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:3T3-L1 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug)
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  Immunohistochemistry (IHC) analyzes of TNF-IP 1 (S122) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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