PSA (L106) polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
PSA (L106) polyclonal antibody Background :
Prostate specific antigen (PSA), also designated γ-seminoprotein, seminin, p30 antigen, semenogelase and kallikrein 3 (KLK3), was first identified as a glycoprotein in human seminal plasma. PSA was determined by sequence similarity to be a member of the kallikrein subfamily of trypsin proteases. PSA is a serine protease that hydrolyzes the major human seminal protein, the seminal plasma mobility inhibitor precursor or semenogelin I (SPMIP or SgI), which leads to semen liquification. PSA production and expression are highest in normal, benign hyperplastic and cancerous tissues of the prostate, although PSA has also been detected in accessory male sex glands and in breast cancer. PSA has been identified as an aid in the early detection of prostate cancer and is a commonly used tumor marker. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PSA (L106) polyclonal antibody detects endogenous levels of PSA protein. Immunogen :
Synthetic peptide, corresponding to amino acids 81-130 of Human PSA. Conjugate :
Unconjugated Modification :
Unmodification
PSA (L106) polyclonal antibody Background :
Prostate specific antigen (PSA), also designated γ-seminoprotein, seminin, p30 antigen, semenogelase and kallikrein 3 (KLK3), was first identified as a glycoprotein in human seminal plasma. PSA was determined by sequence similarity to be a member of the kallikrein subfamily of trypsin proteases. PSA is a serine protease that hydrolyzes the major human seminal protein, the seminal plasma mobility inhibitor precursor or semenogelin I (SPMIP or SgI), which leads to semen liquification. PSA production and expression are highest in normal, benign hyperplastic and cancerous tissues of the prostate, although PSA has also been detected in accessory male sex glands and in breast cancer. PSA has been identified as an aid in the early detection of prostate cancer and is a commonly used tumor marker. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PSA (L106) polyclonal antibody detects endogenous levels of PSA protein. Immunogen :
Synthetic peptide, corresponding to amino acids 81-130 of Human PSA. Conjugate :
Unconjugated Modification :
Unmodification
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Immunohistochemistry (IHC) analyzes of PSA (L106) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.
Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells
PMCID: Pubmed No.:28638477
Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
PMCID: Pubmed No.:28151478
Cancer Targeting Potential of 99mTc-Finasteride in Experimental Model of Prostate Carcinogenesis
PMCID: Pubmed No.:28301260
Growth arrest and DNA-damage-inducible 45 beta (GADD45β) deletion suppresses testosterone-induced prostate hyperplasia in mice
PMCID: Pubmed No.:30195037
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.