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HDAC6 (H1203) polyclonal antibody BS1165
  • Western blot (WB) analysis of HDAC6 (H1203) pAb at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:A375 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug)
  • Immunohistochemistry (IHC) analyzes of HDAC6 (H1203) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Product NameHDAC6 (H1203) polyclonal antibody
Catalog No.BS1165
Swiss-ProtQ9UBN7
Host Rabbit
ReactivityHuman,Mouse,Rat
ApplicationsWB IHC IF
Application_allWB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
BiowMW~ 131, 160 kDa
Alternative NameHistone deacetylase 6; HD6; HDAC 6; KIAA0901; JM21
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodification
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Size Price
50ul $158
100ul $275
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Product Name :
HDAC6 (H1203) polyclonal antibody
Background :
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
HDAC6 (H1203) polyclonal antibody detects endogenous levels of HDAC6 protein.
Immunogen :
Synthetic peptide, corresponding to the C-terminual of Human HDAC6.
Conjugate :
Unconjugated
Modification :
Unmodification
  • Western blot (WB) analysis of HDAC6 (H1203) pAb at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:A375 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug)
  • Immunohistochemistry (IHC) analyzes of HDAC6 (H1203) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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