Product Name :
IFT88 polyclonal antibody Background :
IFT88 (Intraflagellar transport protein 88), also known as TG737 or TTC10 (TPR repeat protein 10), is an 833 amino acid protein that contains 12 TPR repeats and belongs to the TPR family. Expressed in lung, heart, liver, brain, pancreas, kidney and skeletal muscle, IFT88 is thought to interact with other intraflagellar transport proteins and may play a role in the assembly and maintenance of the vertebrate outer segment. Additionally, IFT88 is thought to function as a centrosomal protein that may regulate the G1 to S phase cell cycle transition in non-ciliated cells. Defects in the gene encoding IFT88 may be associated with the pathogenesis of polycystic kidney disease, a genetic disorder that is characterized by the presence of cysts within the kidneys. IFT88 expression is downregulated in hepatocellular carcinomas, suggesting a role for IFT88 in tumor suppression. Multiple isoforms of IFT88 exist due to alternative splicing events. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
IFT88 polyclonal antibody detects endogenous levels of IFT88 protein. Immunogen :
Recombinant protein of human IFT88. Conjugate :
Unconjugated Modification :
Unmodification

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Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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