Product Name :
KIF20A (I524) polyclonal antibody Background :
The Kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual Kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events, including endocytosis and transcytosis. KIF20A (kinesin family member 20A), also known as Rabkinesin-6, RAB6KIFL (Rab6-interacting kinesin-like protein), GG10_2 or MKLP2 (mitotic kinesin-like protein 2), is a 890 amino acid protein that contains one kinesin-motor domain and belongs to the Kinesin-like protein family. KIF20A locates to the Golgi apparatus and interacts with guanosine triphosphate (GTP)-bound forms of RAB 6. KIF20A may be responsible for the retrograde RAB 6 regulated transport of Golgi membranes and related vesicles along microtubules. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
KIF20A(I524) polyclonal antibody detects endogenous levels of KIF20A protein. Immunogen :
Synthetic peptide, corresponding to amino acids 501-550 of Human KIF20A. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of KIF20A (I524) pAb at 1:500 dilution Lane1:SGC7901 whole cell lysate(10ug) Lane2:EC9706 whole cell lysate(10ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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