Product Name :
CD160 (T45) polyclonal antibody Background :
CD160, also known as NK1, BY55 or NK28, is a 181 amino acid lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain. Expressed in small intestine, spleen and functional NK (natural killer) and T cytotoxic lymphocytes, CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells. Additionally, CD160 interacts with HVEM (herpesvirus entry mediator) and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation. Multiple isoforms of CD160 exist due to alternative splicing events. The gene encoding CD160 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CD160 (T45) polyclonal antibody detects endogenous levels of CD160 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 21-70 of Human CD160. Conjugate :
Unconjugated Modification :
Unmodification

• 
  Western blot (WB) analysis of CD160 pAb at 1:1000 dilution Lane1:RAW264.7 whole cell lysate(40ug) Lane2:K562 whole cell lysate(40ug) Lane3:Jurkat whole cell lysate(40ug) Lane4:Myla2059 whole cell lysate(40ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

---

Price/Size :

USD 368/1mg/vial

---

---

Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

---

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

---

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

---

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

---

Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

---