Product Name :
UGT3A2 polyclonal antibody Background :
UDP-glucuronosyltransferase isoenzymes (UGTs) catalyze the glucuronidation of small lipophilic molecules, thereby regulating the bioactivity and metabolic fate of a wide range of endogenous compounds and xenobiotics. Glucuronidation increases the polarity of lipophilic molecules and facilitates their entry into aqueous compartments and, ultimately, their excretion. In essence, glucuronidation provides a protective function by terminating or attenuating the biological activity of its substrates. The UGT3A family of isoenzymes are expressed in liver and kidney, and to a lesser, in the gastrointestinal tract. UGT3A2 (UDP glycosyltransferase 3 family, polypeptide A2) is a 523 amino acid single-pass type I membrane protein that belongs to the UDP-glycosyltransferase family. It has been suggested that members of the UGT3A family may have an important role in the metabolism and elimination of ursodeoxycholic acid, a metabolic byproduct of intestinal bacteria. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
UGT3A2 polyclonal antibody detects endogenous levels of UGT3A2 protein. Immunogen :
Recombinant full length Human UGT3A2. Conjugate :
Unconjugated Modification :
Unmodification

• 
  Western blot analysis of extracts of various cell lines, using UGT3A2 antibody.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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