Product Name :
GPR68 polyclonal antibody Background :
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR68 (G protein-coupled receptor 68), also known as OGR1 (ovarian cancer G-protein coupled receptor 1), is a 365 amino acid multi-pass membrane protein that is expressed in testis, spleen, lung, brain and placenta. Existing as a member of the G protein-coupled receptor family, GPR68 functions as a high affinity receptor for sphingosylphosphorylcholine and is coupled to G proteins that enhance phosphoinositide hydrolysis. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GPR68 polyclonal antibody detects endogenous levels of GPR68 protein. Immunogen :
Recombinant full length Human GPR68. Conjugate :
Unconjugated Modification :
Unmodification
GPR68 polyclonal antibody Background :
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR68 (G protein-coupled receptor 68), also known as OGR1 (ovarian cancer G-protein coupled receptor 1), is a 365 amino acid multi-pass membrane protein that is expressed in testis, spleen, lung, brain and placenta. Existing as a member of the G protein-coupled receptor family, GPR68 functions as a high affinity receptor for sphingosylphosphorylcholine and is coupled to G proteins that enhance phosphoinositide hydrolysis. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GPR68 polyclonal antibody detects endogenous levels of GPR68 protein. Immunogen :
Recombinant full length Human GPR68. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot analysis of extracts of various cell lines, using GPR68 antibody.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.