OPRL1 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
OPRL1 polyclonal antibody Background :
Endogenous opioid peptides and opiates like morphine mediate their cellular effects through membrane bound receptors. Three different types of opioid receptors have been identified, mu-type, delta-type and kappa-type. A fourth opioid receptor, KOR-3 (kappa-type opioid receptor, also designated ORL1- Opioid Receptor Like 1), has been identified. Though closely related genetically to the other opioid receptors, KOR-3 has a distinct pharmacological profile. Nociceptin, the neuropeptide which activates KOR-3, is structurally similar to the kappa-opioid peptide dynorphin A, but quite different in its mode of interaction with its receptor. KOR-3 is widely expressed in the nervous system, and is likely to modulate a broad range of physiological and behavioral functions. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
OPRL1 polyclonal antibody detects endogenous levels of OPRL1 protein. Immunogen :
Recombinant full length Human OPRL1. Conjugate :
Unconjugated Modification :
Unmodification
OPRL1 polyclonal antibody Background :
Endogenous opioid peptides and opiates like morphine mediate their cellular effects through membrane bound receptors. Three different types of opioid receptors have been identified, mu-type, delta-type and kappa-type. A fourth opioid receptor, KOR-3 (kappa-type opioid receptor, also designated ORL1- Opioid Receptor Like 1), has been identified. Though closely related genetically to the other opioid receptors, KOR-3 has a distinct pharmacological profile. Nociceptin, the neuropeptide which activates KOR-3, is structurally similar to the kappa-opioid peptide dynorphin A, but quite different in its mode of interaction with its receptor. KOR-3 is widely expressed in the nervous system, and is likely to modulate a broad range of physiological and behavioral functions. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
OPRL1 polyclonal antibody detects endogenous levels of OPRL1 protein. Immunogen :
Recombinant full length Human OPRL1. Conjugate :
Unconjugated Modification :
Unmodification
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WesternBlot (WB) analysis of OPRL1 polyclonal antibody
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.