Product Name :
NOR-1 (Y419) polyclonal antibody Background :
Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1) and NOR-1 (neuron-derived orphan receptor-1) constitute the NGFI-B subfamily within the nuclear receptor superfamily.The human NOR-1 gene maps to chromosome 9q and encodes a protein which is expressed in heart, skeletal muscle, thymus and spleen as well as in brain, where it is developmentally regulated. Therefore, NOR-1 may be involved in regulating neural differentiation. The NOR-1 gene also undergoes chromosomal translocation with the EWS gene to produce a protein thought to affect pre-mRNA splicing. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
NOR-1 (Y419) polyclonal antibody detects endogenous levels of NOR-1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 389-435 of Human NOR-1. Conjugate :
Unconjugated Modification :
Unmodification
NOR-1 (Y419) polyclonal antibody Background :
Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1) and NOR-1 (neuron-derived orphan receptor-1) constitute the NGFI-B subfamily within the nuclear receptor superfamily.The human NOR-1 gene maps to chromosome 9q and encodes a protein which is expressed in heart, skeletal muscle, thymus and spleen as well as in brain, where it is developmentally regulated. Therefore, NOR-1 may be involved in regulating neural differentiation. The NOR-1 gene also undergoes chromosomal translocation with the EWS gene to produce a protein thought to affect pre-mRNA splicing. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
NOR-1 (Y419) polyclonal antibody detects endogenous levels of NOR-1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 389-435 of Human NOR-1. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of NR4A3 pAb at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug)
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.