Product Name :
STXBP1 polyclonal antibody Background :
Munc18-1 belongs to the Munc18 protein family that also includes Munc18-2 and Munc18-3. These proteins are highly conserved at the amino acid sequence level and play a critical role in membrane fusion. Munc18 proteins control SNARE complex formation and interact with syntaxin. In Munc18-1 knockout mice, neurotransmitter release is completely abolished. In addition, Munc18-1 acts as a molecular chaperone for syntaxin-1, allowing for formation of the SNARE complex at the plasma membrane. Munc18-1 also acts as a regulator of vesicle docking during exocytosis. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
STXBP1 polyclonal antibody detects endogenous levels of STXBP1 protein. Immunogen :
Synthetic peptide, corresponding to Human STXBP1. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of STXBP1 polyclonal antibody at 1:500 dilution Lane1:U-87MG whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:SHSY5Y whole cell lysate(40ug) Lane4:K562 whole cell lysate(40ug) Lane5:RAW264.7 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Mouse(40ug) Lane7:The Brain tissue lysate of Rat(40ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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