Product Name :
ABCC13 polyclonal antibody Background :
The S-100 protein family consists of a group of calcium-binding proteins that are exclusively expressed in vertebrates and exhibit cell and tissue-specific expression. The expression levels of its members differ in various pathological conditions. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation and motility of tumor cells. S-100Z (S100 calcium-binding protein Z) is a 99 amino acid protein that shares 57% and 52% sequence identity with S-100A1 and S-100P, respectively. A dimeric, predominantly α-helical protein, S-100Z contains two EF-hand domains capable of binding calcium ions. Binding of calcium results in conformational changes and exposure of hydrophobic surfaces on the protein. S-100Z interacts with S-100P, and demonstrates highest level of expression in spleen and leukocytes. The S-100Z gene is conserved in chimpanzee, bovine, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q13.3. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4. Storage&Stability :
Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles. Specificity :
ABCC13 polyclonal antibody detects endogenous levels of ABCC13 protein. Immunogen :
Synthetic peptide, corresponding to Human ABCC13. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of ABCC13 polyclonal antibody at 1:500 dilution LaneA:HT29 whole cell lysate

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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