Product Name :
Ubiquilin 3 polyclonal antibody Background :
Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of this small, 76 amino acid protein is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. Many ubiquitin-like proteins function as post-translational protein modifiers, such as members of the SUMO protein family, however some ubiquitin-like proteins regulate protein-protein interactions and cell cycle events, thereby functioning outside of the traditional ubiquitination pathway. UBQLN3 (Ubiquilin-3) is a 654 amino acid protein containing one N-terminal ubiquitin-like (UBQ) domain and one C-terminal UBA domain. With expression limited to testis, it has been suggested that UBQLN3 may associate with testis-specific cyclin A1 and/or cyclin A to regulate the cell cycle during spermatogenesis. Similarly, a family member related to UBQLN3, namely PLIC-1, also known as Ubiquilin-1, may also play a critical role in cell cycle regulation. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Ubiquilin 3 polyclonal antibody detects endogenous levels of Ubiquilin 3 protein. Immunogen :
Synthetic peptide, corresponding to Human Ubiquilin 3. Conjugate :
Unconjugated Modification :
Unmodification

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  Western blot (WB) analysis of Ubiquilin 3 polyclonal antibody at 1:500 dilution LaneA:A549 whole cell lysate

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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