Product Name :
MRPL41 polyclonal antibody Background :
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L41 (mitochondrial ribosomal protein L41), also known as cell proliferation-inducing gene 3 protein and BMRP (Bcl-2-interacting mitochondrial ribosomal protein L41), is a 137 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. Expressed in liver, testis, kidney and thymus, MRP-L41 is in-volved in the cell cycle and apoptosis. Possibly by stabilizing p21 and p27, MRP-L41 has the ability to arrest the cell cycle in the G1 phase. MRP-L41 also enhances p53 stability, therefore contributing to p53-induced apoptosis in response to growth-inhibitory conditions Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
MRPL41 polyclonal antibody detects endogenous levels of MRPL41 protein. Immunogen :
Synthetic peptide, corresponding to Human MRPL41. Conjugate :
Unconjugated Modification :
Unmodification

• 
  Western blot analysis of lysates of human liver tissue, using MRPL41 polyclonal antibody.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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