Contact us : info@bioworlde.com
Home > Product > Primary Antibodies
Bcl-2 Polyclonal Antibody BS65626
  • Sample: Lane 1: Spleen (Rat) Lysate at 40 ug Lane 2: Bone (Rat) Lysate at 40 ug Primary: Anti- Bcl-2 at 1/1000 dilution
  • Sample: Lane 1: Spleen (Mouse) Lysate at 40 ug Lane 2: Lymph node (Mouse) Lysate at 40 ug Lane 3: Bone (Mouse) Lysate at 40 ug Lane 4: Thyroid gland (Mouse) Lysate at 40 ug Lane 5: Spleen (Rat) Lysate at 40 ug Primary: Anti- Bcl-2 at 1/1000 dilution
Product NameBcl-2 Polyclonal Antibody
Catalog No.BS65626
Swiss-ProtP49950
Host Rabbit
ReactivityMouse, Rat, (predicted: Human, )
ApplicationsWB,IHC-P,
Application_allWB=1:500-2000 
BiowMW26 kD
Alternative NameApoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2; BCL2_HUMAN.
Purification&Purityaffinity purified by Protein A
ConjugateUnconjugated
ModificationUnmodification
Browse similar products>>
Size Price
50ul $208
100ul $358
Add to cart My orders
Product Name :
Bcl-2 Polyclonal Antibody
Background :
The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8).
Product :
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
Bcl-2 Polyclonal Antibody detects endogenous levels of Bcl-2 protein.
Immunogen :
KLH conjugated synthetic peptide derived from human Bcl-2
Conjugate :
Unconjugated
Modification :
Unmodification
  • Sample: Lane 1: Spleen (Rat) Lysate at 40 ug Lane 2: Bone (Rat) Lysate at 40 ug Primary: Anti- Bcl-2 at 1/1000 dilution
  • Sample: Lane 1: Spleen (Mouse) Lysate at 40 ug Lane 2: Lymph node (Mouse) Lysate at 40 ug Lane 3: Bone (Mouse) Lysate at 40 ug Lane 4: Thyroid gland (Mouse) Lysate at 40 ug Lane 5: Spleen (Rat) Lysate at 40 ug Primary: Anti- Bcl-2 at 1/1000 dilution
Alpha fetoprotein mediates HBx induced carcinogenesis in the hepatocyte cytoplasm PMCID:    Pubmed No.:25846475 Multisite mutation of monomer survivin with enhanced effect on apoptosis regulation of breast cancer cells PMCID:    Pubmed No.:25661346 Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents PMCID:    Pubmed No.:25841199 Synthesis and pharmacological evaluation of dehydroabietic acid thiourea derivatives containing bisphosphonate moiety as an inducer of apoptosis PMCID:    Pubmed No.:26706349 Long non-coding RNA LINC00968 acts as oncogene in NSCLC by activating the Wnt signaling pathway PMCID:    Pubmed No.:28926089 MicroRNA‐146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury PMCID:    Pubmed No.:27400799 n-3 Polyunsaturated fatty acids protect against pancreatic β-cell damage due to ER stress and prevent diabetes development PMCID:    Pubmed No.:26080997 Gas1 up-regulation is inducible and contributes to cell apoptosis in reactive astrocytes in the substantia nigra of LPS and MPTP models PMCID:    Pubmed No.:27391369 LZ-106, a novel analog of enoxacin, inducing apoptosis via activation of ROS-dependent DNA damage response in NSCLCs PMCID:    Pubmed No.:27012423 The overexpression and nuclear translocation of Trx-1 during hypoxia confers on HepG2 cells resistance to DDP, and GL-V9 reverses the resistance by suppressing the Trx-1/Ref-1 axis PMCID:    Pubmed No.:25656992 Smad4 controls bone homeostasis through regulation of osteoblast/osteocyte viability PMCID:    Pubmed No.:27585718 Lateral intracerebroventricular injection of Apelin-13 inhibits apoptosis after cerebral ischemia/reperfusion injury PMCID:    Pubmed No.:26109951 Low Dose of Bisphenol A Activates NF-κB/IL-6 Signals to Increase Malignancy of Neuroblastoma Cells PMCID:    Pubmed No.:27866306 Enhancing the anti-multiple myeloma efficiency in a cancer stem cell xenograft model by conjugating the ABCG2 antibody with microbubbles for a targeted delivery of ultrasound mediated epirubicin PMCID:    Pubmed No.:28232025 Autophagy promotes fibrosis and apoptosis in the peritoneum during long‐term peritoneal dialysis PMCID:    Pubmed No.:29077259 Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy PMCID:    Pubmed No.:28388958 High glucose concentration induces endothelial cell proliferation by regulating cyclin‐D2‐related miR‐98 PMCID:    Pubmed No.:26840039 Foxc2 enhances proliferation and inhibits apoptosis through activating Akt/mTORC1 signaling pathway in mouse preadipocytes PMCID:    Pubmed No.:26113535 Bound polyphenol from foxtail millet bran induces apoptosis in HCT-116 cell through ROS generation PMCID:    Pubmed No.:34975288 Deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus PMCID:    Pubmed No.:27608977 The neuroprotective effect of a novel agent N2 on rat cerebral ischemia associated with the activation of PI3K/Akt signaling pathway PMCID:    Pubmed No.:25725335 Alpinetin inhibits lung cancer progression and elevates sensitization drug-resistant lung cancer cells to cis-diammined dichloridoplatium PMCID:    Pubmed No.:26604699 Neuroprotective effects of hydrogen sulfide on sodium azide-induced oxidative stress in PC12 cells PMCID:    Pubmed No.:29115393 Neuroprotective effects of hydrogen sulfide on sodium azide-induced oxidative stress in PC12 cells PMCID:    Pubmed No.:29115393 Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents PMCID:    Pubmed No.:27138035 Triptolide induces Sertoli cell apoptosis in mice via ROS/JNK-dependent activation of the mitochondrial pathway and inhibition of Nrf2-mediated antioxidant response PMCID:    Pubmed No.:28905938 Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects of the mTOR Inhibitor Everolimus against Melanoma PMCID:    Pubmed No.:28054548 Autophagy regulates intracerebral hemorrhage induced neural damage via apoptosis and NF-κB pathway PMCID:    Pubmed No.:26964766 The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy PMCID:    Pubmed No.:29277549 Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic Injury PMCID:    Pubmed No.:26106430 Orientin alleviates cognitive deficits and oxidative stress in Aβ1–42-induced mouse model of Alzheimer's disease PMCID:    Pubmed No.:25497709 The NLRP3 inflammasome is dispensable for ER stress-induced pancreatic β-cell damage in Akita mice PMCID:    Pubmed No.:26361146 PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway PMCID:    Pubmed No.:28304296 Study on the mechanism of AMPK signaling pathway and its effect on apoptosis of human hepatocellular carcinoma SMMC-7721 cells by curcumin. PMCID:    Pubmed No.:28338175 NOAD, a novel nitric oxide donor, induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma Bel-7402 cells PMCID:    Pubmed No.:26001517 Inhibition of green tea polyphenol EGCG((−)-epigallocatechin-3-gallate) on the proliferation of gastric cancer cells by suppressing canonical wnt/β-catenin signalling pathway PMCID:    Pubmed No.:27338284 MCM2 is a therapeutic target of lovastatin in human non-small cell lung carcinomas PMCID:    Pubmed No.:25738322 Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice PMCID:    Pubmed No.:26064905 Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway PMCID:    Pubmed No.:28734031 The stress-response molecule NR4A1 resists ROS-induced pancreatic β-cells apoptosis via WT1 PMCID:    Pubmed No.:28342843 Synthesis, antiproliferative and apoptosis-inducing effects of novel asiatic acid derivatives containing α-aminophosphonates PMCID:    Pubmed No.:24262379 A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson′s disease by increasing expression of BNDF PMCID:    Pubmed No.:26453833 Study on the mitochondrial apoptosis pathways of small cell lung cancer H446 cells induced by Trichinella spiralis muscle larvae ESPs PMCID:    Pubmed No.:28073393 Electroacupuncture improves neurobehavioral function and brain injury in rat model of intracerebral hemorrhage PMCID:    Pubmed No.:28395933 Clostridium butyricum pretreatment attenuates cerebral ischemia/reperfusion injury in mice via anti-oxidation and anti-apoptosis PMCID:    Pubmed No.:26733300 Recombinant hirudin suppresses the viability, adhesion, migration and invasion of Hep-2 human laryngeal cancer cells PMCID:    Pubmed No.:25592110 Blocking B7-1/CD28 Pathway Diminished Long-Range Brain Damage by Regulating the Immune and Inflammatory Responses in a Mouse Model of Intracerebral Hemorrhage PMCID:    Pubmed No.:26980009 Protective Effect of l -Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway PMCID:    Pubmed No.:26164708 FK506 protects heart function via increasing autophagy after myocardial infarction in mice PMCID:    Pubmed No.:28965948 Annosquacin B induces mitochondrial apoptosis in multidrug resistant human breast cancer cell line MCF-7/ADR through selectively modulating MAPKs pathways PMCID:    Pubmed No.:27450387 Astragalus polysaccharides exert protective effects in newborn rats with bronchopulmonary dysplasia by upregulating the expression of EGFL7 in lung tissue PMCID:    Pubmed No.:25270395 Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model PMCID:    Pubmed No.:25572806 Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis PMCID:    Pubmed No.:26014479 Suppression of murine experimental autoimmune encephalomyelitis development by 1,25-dihydroxyvitamin D3 with autophagy modulation PMCID:    Pubmed No.:25773147 Protective Efficacy of Vitamins C and E on p,p′-DDT-Induced Cytotoxicity via the ROS-Mediated Mitochondrial Pathway and NF-κB/FasL Pathway PMCID:    Pubmed No.:25464339 A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model PMCID:    Pubmed No.:28342971 Lithium chloride administration prevents spatial learning and memory impairment in repeated cerebral ischemia-reperfusion mice by depressing apoptosis and increasing BDNF expression in hippocampus PMCID:    Pubmed No.:26031381 Downregulation of hTERT: An Important As2O3 Induced Mechanism of Apoptosis in Myelodysplastic Syndrome PMCID:    Pubmed No.:25415199 SENP1 inhibits the IH-induced apoptosis and nitric oxide production in BV2 microglial cells PMCID:    Pubmed No.:26499079 miR‐1273g‐3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV‐related liver fibrosis PMCID:    Pubmed No.:27423040 Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1 PMCID:    Pubmed No.:28991675 Downregulation of angiogenin inhibits the growth and induces apoptosis in human bladder cancer cells through regulating AKT/mTOR signaling pathway PMCID:    Pubmed No.:25564356 Depleted aldehyde dehydrogenase 1A1 (ALDH1A1) reverses cisplatin resistance of human lung adenocarcinoma cell A549/DDP PMCID:    Pubmed No.:27813328 Neuroprotection by peripheral nerve electrical stimulation and remote postconditioning against acute experimental ischaemic stroke PMCID:    Pubmed No.:25819636 Triptolide exerts pro-apoptotic and cell cycle arrest activity on drug-resistant human lung cancer A549/Taxol cells via modulation of MAPK and PI3K/Akt signaling pathways PMCID:    Pubmed No.:27900040 Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy PMCID:    Pubmed No.:27956235 Self-Assembling RADA16-I Peptide Hydrogel Scaffold Loaded with Tamoxifen for Breast Reconstruction PMCID:    Pubmed No.:28691024 Silencing thioredoxin1 exacerbates damage of astrocytes exposed to OGD/R by aggravating apoptosis through the Actin–Ras2–cAMP–PKA pathway PMCID:    Pubmed No.:29073813 Silencing thioredoxin1 exacerbates damage of astrocytes exposed to OGD/R by aggravating apoptosis through the Actin–Ras2–cAMP–PKA pathway PMCID:    Pubmed No.:29073813 ZFX Facilitates Cell Proliferation and Imatinib Resistance in Chronic Myeloid Leukemia Cells PMCID:    Pubmed No.:26912059 Glioma targeting peptide in combination with the P53 C terminus inhibits glioma cell proliferation in vitro PMCID:    Pubmed No.:28879517 Gastrodin prevents steroid-induced osteonecrosis of the femoral head in rats by anti-apoptosis PMCID:    Pubmed No.:30704229 Defective autophagy is associated with neuronal injury in a mouse model of multiple sclerosis PMCID:    Pubmed No.:28086065 Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205 PMCID:    Pubmed No.:27895312 BM microenvironmental protection of CML cells from imatinib through Stat5/NF-κB signaling and reversal by Wogonin PMCID:    Pubmed No.:27027438 PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells PMCID:    Pubmed No.:27147579 MicroRNA-181 functions as a tumor suppressor in non-small cell lung cancer (NSCLC) by targeting Bcl-2 PMCID:    Pubmed No.:25524579 miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A PMCID:    Pubmed No.:26023735 miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A PMCID:    Pubmed No.:26023735 Salinomycin radiosensitizes human nasopharyngeal carcinoma cell line CNE-2 to radiation PMCID:    Pubmed No.:26209294 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition PMCID:    Pubmed No.:26316083 ING4 expressing oncolytic vaccinia virus promotes anti-tumor efficiency and synergizes with gemcitabine in pancreatic cancer PMCID:    Pubmed No.:29137298 The long non-coding RNA CRNDE acts as a ceRNA and promotes glioma malignancy by preventing miR-136-5p-mediated downregulation of Bcl-2 and Wnt2 PMCID:    Pubmed No.:29152149 Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro PMCID:    Pubmed No.:26707712 Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells PMCID:    Pubmed No.:25394466 Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells PMCID:    Pubmed No.:25394466 Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells PMCID:    Pubmed No.:25394466 Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells PMCID:    Pubmed No.:26035796 Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways PMCID:    Pubmed No.:26503828 Malibatol A protects against brain injury through reversing mitochondrial dysfunction in experimental stroke PMCID:    Pubmed No.:25447763 Human Umbilical Cord Mesenchymal Stem Cells Protect Against SCA3 by Modulating the Level of 70 kD Heat Shock Protein PMCID:    Pubmed No.:28667374 Apelin-13 protects against apoptosis by activating AMP-activated protein kinase pathway in ischemia stroke PMCID:    Pubmed No.:26631263 A novel small molecule compound diaporine inhibits breast cancer cell proliferation via promoting ROS generation PMCID:    Pubmed No.:27543689 Interval exercise training increases LIF expression and prevents myocardial infarction-induced skeletal muscle atrophy in rats PMCID:    Pubmed No.:29223542 FV‐429 induces apoptosis and inhibits glycolysis by inhibiting Akt‐mediated phosphorylation of hexokinase II in MDA‐MB‐231 cells PMCID:    Pubmed No.:26258875 MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A PMCID:    Pubmed No.:28123563 Exosomal miR-1910-3p promotes proliferation, metastasis, and autophagy of breast cancer cells by targeting MTMR3 and activating the NF-κB signaling pathway PMCID:    Pubmed No.:32531321 Long non-coding RNA ESCCAL-1 promotes esophageal squamous cell carcinoma by down regulating the negative regulator of APOBEC3G PMCID:    Pubmed No.:32905814 Potent effects of dioscin against hepatocellular carcinoma through regulating TP53‐induced glycolysis and apoptosis regulator (TIGAR)‐mediated apoptosis, autophagy, and DNA damage PMCID:    Pubmed No.:30710454 A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway PMCID:    Pubmed No.:34887997 Piperazine-Derived α1D/1A Antagonist 1- Benzyl-N- (3-(4- (2-Methoxyphenyl) Piperazine-1-yl) Propyl) -1H- Indole-2- Carboxamide Induces Apoptosis in Benign Prostatic Hyperplasia Independently of α1-Adrenoceptor Blocking PMCID:    Pubmed No.:33584271 Pyridostigmine alleviates cardiac dysfunction via improving mitochondrial cristae shape in a mouse model of metabolic syndrome PMCID:    Pubmed No.:30633969 Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways PMCID:    Pubmed No.:32573644 A novel drug-free strategy of nano-pulse stimulation sequence (NPSS) in oral cancer therapy: In vitro and in vivo study PMCID:    Pubmed No.:29719274 Reversal Effects of Bound Polyphenol from Foxtail Millet Bran on Multidrug Resistance in Human HCT-8/Fu Colorectal Cancer Cell PMCID:    Pubmed No.:29730933 Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells PMCID:    Pubmed No.:33663206 Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells PMCID:    Pubmed No.:33663206 Follicular fluid exosomes: Important modulator in proliferation and steroid synthesis of porcine granulosa cells PMCID:    Pubmed No.:33908671 Histone deacetylase 8 inhibition alleviates cholestatic liver injury and fibrosis PMCID:    Pubmed No.:33130126 The RhoA/ROCK pathway mediates high glucose-induced cardiomyocyte apoptosis via oxidative stress, JNK, and p38MAPK pathways PMCID:    Pubmed No.:29745021 The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling PMCID:    Pubmed No.:31884423 HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation PMCID:    Pubmed No.:33882455 Toosendanin Shows Potent Efficacy Against Human Ovarian Cancer through Caspase-Dependent Mitochondrial Apoptotic Pathway PMCID:    Pubmed No.:34521317 Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis PMCID:    Pubmed No.:32920515 A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway PMCID:    Pubmed No.:30153443 Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth PMCID:    Pubmed No.:32128976 Constitutive activity of GPR26 regulated by ubiquitin‐dependent degradation and its antitumor role PMCID:    Pubmed No.:33577134 Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice PMCID:    Pubmed No.:29867447 Integrating bioinformatics with pharmacological evaluation for illustrating the action mechanism of herbal formula Jiao'e mixture in suppressing lung carcinoma PMCID:    Pubmed No.:34400263 Diterpene Ginkgolides Meglumine Injection inhibits apoptosis induced by optic nerve crush injury via modulating MAPKs signaling pathways in retinal ganglion cells PMCID:    Pubmed No.:34181957 Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling PMCID:    Pubmed No.:32848779 Protective effects of Salidroside on cardiac function in mice with myocardial infarction PMCID:    Pubmed No.:31792327 Comparison of the sensitivity of Western blotting between PVDF and NC membranes PMCID:    Pubmed No.:34103620 The biphasic effects of the oxLDL/β2GPI/anti-β2GPI complex on VSMC proliferation and apoptosis PMCID:    Pubmed No.:30738928 Profiles of messenger RNAs and MicroRNAs in hypoxia-induced hepatic stellate cells PMCID:    Pubmed No.:34734003 Lentivirus-Mediated HDAC3 Inhibition Attenuates Oxidative Stress in APPswe/PS1dE9 Mice PMCID:    Pubmed No.:29376873 Vitamin D3 supplementation improves testicular function in diabetic rats through peroxisome proliferator‐activated receptor‐γ/transforming growth factor‐beta 1/nuclear factor‐kappa B PMCID:    Pubmed No.:29953732 Prodromal Alzheimer’s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer’s Pathology PMCID:    Pubmed No.:33343276 The novel GLP-1/GIP dual agonist DA3-CH is more effective than liraglutide in reducing endoplasmic reticulum stress in diabetic rats with cerebral ischemia-reperfusion injury PMCID:    Pubmed No.:33500109 Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells PMCID:    Pubmed No.:33549076 (−)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway PMCID:    Pubmed No.:30741544 Luteolin attenuates high glucose-induced podocyte injury via suppressing NLRP3 inflammasome pathway PMCID:    Pubmed No.:30935950 Epidermal growth factor‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) suppressed the growth of hepatocellular carcinoma cells by promoting Semaphorin 3B(SEMA3B) PMCID:    Pubmed No.:30972979 LncRNA SNHG6 Inhibits Apoptosis by Regulating EZH2 Expression via the Sponging of MiR-101-3p in Esophageal Squamous-Cell Carcinoma PMCID:    Pubmed No.:33192074 Echinocystic acid provides a neuroprotective effect via the PI3K/AKT pathway in intracerebral haemorrhage mice PMCID:    Pubmed No.:32055597 Echinocystic acid, a natural plant extract, alleviates cerebral ischemia/reperfusion injury via inhibiting the JNK signaling pathway PMCID:    Pubmed No.:31425684 Rosmarinic acid elicits neuroprotection in ischemic stroke via Nrf2 and heme oxygenase 1 signaling PMCID:    Pubmed No.:30323140 RNPS1 inhibition aggravates ischemic brain injury and promotes neuronal death PMCID:    Pubmed No.:31831174 Methylene Blue Exerts Anticonvulsant and Neuroprotective Effects on Self-Sustaining Status Epilepticus (SSSE) Induced by Prolonged Basolateral Amygdala Stimulation in Wistar Rats PMCID:    Pubmed No.:29307885 Mitochondrial targeting of TR3 is involved in TPA induced apoptosis in breast cancer cells PMCID:    Pubmed No.:30641217 Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model PMCID:    Pubmed No.:30017231 Effect of Heat Treatment on the Anticancer Activity of Houttuynia cordata Thunb Aerial Stem Extract in Human Gastric Cancer SGC-7901 Cells PMCID:    Pubmed No.:32180441 -Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells PMCID:    Pubmed No.:30363706 The novel GLP-1/GIP dual receptor agonist DA3-CH is neuroprotective in the pilocarpine-induced epileptogenesis rat model PMCID:    Pubmed No.:31121474 Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus PMCID:    Pubmed No.:29549796 Semaglutide-mediated protection against Aβ correlated with enhancement of autophagy and inhibition of apotosis PMCID:    Pubmed No.:33222922 Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells PMCID:    Pubmed No.:32424110 Expression of brain-derived neurotrophic factor in kidneys from normal and cyclosporine-treated rats PMCID:    Pubmed No.:29540150 Ethanol Extract of Hizikia fusiforme Induces Apoptosis in B16F10 Mouse Melanoma Cells through ROS-Dependent Inhibition of the PI3K/Akt Signaling Pathway PMCID:    Pubmed No.:32458633 Maraviroc, an inhibitor of chemokine receptor type 5, alleviates neuroinflammatory response after cerebral Ischemia/reperfusion injury via regulating MAPK/NF-κB signaling PMCID:    Pubmed No.:35395466 Translocator protein (18 kDa) regulates the microglial phenotype in Parkinson’s disease through P47 PMCID:    Pubmed No.:35475466 Specific bFGF targeting of KIM-1 in ischemic kidneys protects against renal ischemia reperfusion injury in rats PMCID:    Pubmed No.:35615568 Cardioprotection Attributed to Aerobic Exercise-Mediated Inhibition of ALCAT1 and Oxidative Stress-Induced Apoptosis in MI Rats PMCID:    Pubmed No.:36140351 Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor PMCID:    Pubmed No.:36579729 (+)-Borneol exerts neuroprotective effects via suppressing the NF-κB pathway in the pilocarpine-induced epileptogenesis rat model PMCID:    Pubmed No.:37127175
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
COPYRIGHT © 2015-2018 Bioworld Technology, Inc. All rights reserved POLYCLONAL AND MONOCLONAL ANTIBODY CENTER