Product Name :
CYP2E1 polyclonal antibody Background :
Cytochrome P450 2E1, metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CYP2E1 polyclonal antibody detects endogenous levels of CYP2E1 protein. Immunogen :
Synthetic peptide, corresponding to Human CYP2E1. Conjugate :
Unconjugated Modification :
Unmodification
CYP2E1 polyclonal antibody Background :
Cytochrome P450 2E1, metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CYP2E1 polyclonal antibody detects endogenous levels of CYP2E1 protein. Immunogen :
Synthetic peptide, corresponding to Human CYP2E1. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of CYP2E1 polyclonal antibody at 1:1000 dilution Lane1:Pancl whole cell lysate(40ug) Lane2:A375 whole cell lysate(40ug) Lane3:LO2 whole cell lysate(40ug) Lane4:HEK293T whole cell lysate(40ug) Lane5:A549 whole cell lysate(40ug)
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Western blot (WB) analysis of CYP2E1 polyclonal antibody at 1:1000 dilution Lane1:The Liver tissue lysate of Rat(40ug) Lane2:The Liver tissue lysate of Mouse(40ug) Lane3:The Kidney tissue lysate of Rat(40ug)
Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin gallate
PMCID: Pubmed No.:36028100
Species Difference in the Metabolism of Mulberrin in Vitro and Its Inhibitory Effect on Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes
PMCID: Pubmed No.:36184449
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.