Sirtuin 2 aggravates postischemic liver injury by deacetylating mitogen‐activated protein kinase phosphatase‐1 PMCID:    Pubmed No.:27532371 Blood-brain barrier dysfunction induced by silica NPs in vitro and in vivo: Involvement of oxidative stress and Rho-kinase/JNK signaling pathways PMCID:    Pubmed No.:28081460 Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel PMCID:    Pubmed No.:28951460 TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways PMCID:    Pubmed No.:27669982 Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer PMCID:    Pubmed No.:26649143 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation PMCID:    Pubmed No.:28076833 Isorhapontigenin induced cell growth inhibition and apoptosis by targeting EGFR-related pathways in prostate cancer PMCID:    Pubmed No.:28422286 Osteoinduction and long-term osseointegration promoted by combined effects of nitrogen and manganese elements in high nitrogen nickel-free stainless steel PMCID:    Pubmed No.:32262962 Self-assembling nanofibers improve cognitive impairment in a transgenic mice model of Alzheimer's disease PMCID:    Pubmed No.:24103374 Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway PMCID:    Pubmed No.:24076374 Cardioprotection of Vitexin on Myocardial Ischemia/Reperfusion Injury in Rat via Regulating Inflammatory Cytokines and MAPK Pathway PMCID:    Pubmed No.:24228599 Melatonin promotes the acquisition of neural identity through ERK1/2 activation PMCID:    Pubmed No.:24942200 The IL-6-STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression. PMCID:    Pubmed No.:24946088 Biochanin A attenuates LPS-induced pro-inflammatory responses and inhibits the activation of the MAPK pathway in BV2 microglial cells PMCID:    Pubmed No.:25483920 Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia PMCID:    Pubmed No.:25319672 Modulatory Effects of Vasoactive Intestinal Peptide on Intestinal Mucosal Immunity and Microbial Community of Weaned Piglets Challenged by an Enterotoxigenic Escherichia coli (K88). PMCID:    Pubmed No.:25101851 Expression of ERK and p-ERK proteins of ERK signaling pathway in the kidneys of fluoride-exposed carp (Cyprinus carpio). PMCID:    Pubmed No.:25190107 Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer PMCID:    Pubmed No.:25241857 Diosgenin inhibits superoxide generation in FMLP-activated mouse neutrophils via multiple pathways PMCID:    Pubmed No.:25246240 PM2. 5‐induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF‐κB‐dependent pathway PMCID:    Pubmed No.:25876056 Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells PMCID:    Pubmed No.:26035796 Ruscogenin suppresses mouse neutrophil activation: Involvement of protein kinase A pathway PMCID:    Pubmed No.:26134424 Inhibitory effects of Chikusetsusaponin IVa on lipopolysaccharide-induced pro-inflammatory responses in THP-1 cells. PMCID:    Pubmed No.:26157065 Fluid Shear Stress Inhibits TNF-α-induced Osteoblast Apoptosis via ERK5 Signaling Pathway PMCID:    Pubmed No.:26325467 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition PMCID:    Pubmed No.:26316083 Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways PMCID:    Pubmed No.:26503828 Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons. PMCID:    Pubmed No.:26363976 DGAEE, a newly synthesized derivative of glycyrrhetinic acid, potently attenuates mouse septic shock via its main metabolite DGA in an IL-10-dependent manner PMCID:    Pubmed No.:26456500 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function PMCID:    Pubmed No.:26554390 Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer PMCID:    Pubmed No.:26649143 Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells PMCID:    Pubmed No.:26708214 Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion. PMCID:    Pubmed No.:26849940 MicroRNA-9 regulates cardiac fibrosis by targeting PDGFR-β in rats PMCID:    Pubmed No.:26896308 Dynamic monitoring of GPER-mediated estrogenic effects in breast cancer associated fibroblasts: an alternative role of estrogen in mammary carcinoma development PMCID:    Pubmed No.:27016131 Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways PMCID:    Pubmed No.:27060196 Biochanin A attenuates LPS-induced pro-inflammatory responses and inhibits the activation of the MAPK pathway in BV2 microglial cells PMCID:    Pubmed No.:25483920 Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia PMCID:    Pubmed No.:25319672 Modulatory Effects of Vasoactive Intestinal Peptide on Intestinal Mucosal Immunity and Microbial Community of Weaned Piglets Challenged by an Enterotoxigenic Escherichia coli (K88). PMCID:    Pubmed No.:25101851 Expression of ERK and p-ERK proteins of ERK signaling pathway in the kidneys of fluoride-exposed carp (Cyprinus carpio). PMCID:    Pubmed No.:25190107 Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer PMCID:    Pubmed No.:25241857 Diosgenin inhibits superoxide generation in FMLP-activated mouse neutrophils via multiple pathways PMCID:    Pubmed No.:25246240 Self-assembling nanofibers improve cognitive impairment in a transgenic mice model of Alzheimer's disease PMCID:    Pubmed No.:24103374 Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway PMCID:    Pubmed No.:24076374 Cardioprotection of Vitexin on Myocardial Ischemia/Reperfusion Injury in Rat via Regulating Inflammatory Cytokines and MAPK Pathway PMCID:    Pubmed No.:24228599 Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways PMCID:    Pubmed No.:26503828 Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons. PMCID:    Pubmed No.:26363976 DGAEE, a newly synthesized derivative of glycyrrhetinic acid, potently attenuates mouse septic shock via its main metabolite DGA in an IL-10-dependent manner PMCID:    Pubmed No.:26456500 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function PMCID:    Pubmed No.:26554390 Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer PMCID:    Pubmed No.:26649143 Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells PMCID:    Pubmed No.:26708214 Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion. PMCID:    Pubmed No.:26849940 MicroRNA-9 regulates cardiac fibrosis by targeting PDGFR-β in rats PMCID:    Pubmed No.:26896308 Dynamic monitoring of GPER-mediated estrogenic effects in breast cancer associated fibroblasts: an alternative role of estrogen in mammary carcinoma development PMCID:    Pubmed No.:27016131 Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways PMCID:    Pubmed No.:27060196 Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma PMCID:    Pubmed No.:29075359 Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons PMCID:    Pubmed No.:26363976 Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell PMCID:    Pubmed No.:28280522 SP1-mediated microRNA-520d-5p suppresses tumor growth and metastasis in colorectal cancer by targeting CTHRC1 PMCID:    Pubmed No.:26101709 17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway PMCID:    Pubmed No.:25403930 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function PMCID:    Pubmed No.:26349994 Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway PMCID:    Pubmed No.:27799770 The study of traditional Chinese medical elongated-needle therapy promoting neurological recovery mechanism after spinal cord injury in rats PMCID:    Pubmed No.:27085942 Vitexin protects brain against ischemia/reperfusion injury via modulating mitogen-activated protein kinase and apoptosis signaling in mice PMCID:    Pubmed No.:25837275 Blockade of Serotonin 5-HT2A Receptors Suppresses Behavioral Sensitization and Naloxone-Precipitated Withdrawal Symptoms in Morphine-Treated Mice PMCID:    Pubmed No.:28082900 Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer PMCID:    Pubmed No.:25928008 Structural mechanisms underlying sequence-dependent variations in GAG affinities of decorin binding protein A, a Borrelia burgdorferi adhesin PMCID:    Pubmed No.:25695518 Syndecan-4 Signaling Is Required for Exercise-Induced Cardiac Hypertrophy PMCID:    Pubmed No.:26835698 IGF-1/IGF-1R/ hsa-let-7c axis regulates the committed differentiation of stem cells from apical papilla PMCID:    Pubmed No.:27833148 Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/NF-κB inactivation PMCID:    Pubmed No.:28150717 Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation PMCID:    Pubmed No.:26477505 The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow PMCID:    Pubmed No.:29118325 IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway PMCID:    Pubmed No.:26549519 DGAEE, a newly synthesized derivative of glycyrrhetinic acid, potently attenuates mouse septic shock via its main metabolite DGA in an IL-10-dependent manner PMCID:    Pubmed No.:26456500 DGAEE, a newly synthesized derivative of glycyrrhetinic acid, potently attenuates mouse septic shock via its main metabolite DGA in an IL-10-dependent manner PMCID:    Pubmed No.:26456500 Ruscogenin suppresses mouse neutrophil activation: Involvement of protein kinase A pathway PMCID:    Pubmed No.:26134424 Frequent amplification of PTP1B is associated with poor survival of gastric cancer patients PMCID:    Pubmed No.:25590580 Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF‐9/MAPK/Smad pathway PMCID:    Pubmed No.:28346732 Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF‐9/MAPK/Smad pathway PMCID:    Pubmed No.:28346732 GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis PMCID:    Pubmed No.:28902352 PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-κB-dependent pathway PMCID:    Pubmed No.:25876056 Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition PMCID:    Pubmed No.:27649624 Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells PMCID:    Pubmed No.:26708214 Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways PMCID:    Pubmed No.:27261558 MicroRNA-132 upregulation promotes matrix degradation in intervertebral disc degeneration PMCID:    Pubmed No.:28793234 Biochanin A Protects Against Lipopolysaccharide-Induced Damage of Dopaminergic Neurons Both In Vivo and In Vitro via Inhibition of Microglial Activation PMCID:    Pubmed No.:27417698 Alpha-Tomatine Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated Macrophages PMCID:    Pubmed No.:25772114 Naringin prevents carbon tetrachloride-induced acute liver injury in mice PMCID:    Pubmed No.:36559593 Potent effects of dioscin against thioacetamide-induced liver fibrosis through attenuating oxidative stress in turn inhibiting inflammation, TGF-β/Smad and MAPK signaling pathways PMCID:    Pubmed No.:28070230 Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion PMCID:    Pubmed No.:26849940 High PHLPP expression is associated with better prognosis in patients with resected lung adenocarcinoma PMCID:    Pubmed No.:26463718 Biochanin A attenuates LPS-induced pro-inflammatory responses and inhibits the activation of the MAPK pathway in BV2 microglial cells PMCID:    Pubmed No.:25483920 Astragaloside IV prevents kidney injury caused by iatrogenic hyperinsulinemia in a streptozotocin‑induced diabetic rat model PMCID:    Pubmed No.:29207011 Daphnetin reduces endotoxin lethality in mice and decreases LPS-induced inflammation in Raw264.7 cells via suppressing JAK/STATs activation and ROS production PMCID:    Pubmed No.:28409189 Elevated levels of calcitonin gene-related peptide in upper spinal cord promotes sensitization of primary trigeminal nociceptive neurons PMCID:    Pubmed No.:27746346 Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer PMCID:    Pubmed No.:25241857 The Red Nucleus TNF-α Participates in the Initiation and Maintenance of Neuropathic Pain Through Different Signaling Pathways PMCID:    Pubmed No.:25952358 Tetrandrine inhibits migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes through down-regulating the expressions of Rac1, Cdc42, and RhoA GTPases and activation of the PI3K/Akt and JNK signaling pathways PMCID:    Pubmed No.:26614458 Disrupting nNOS-PSD-95 coupling in the hippocampal dentate gyrus promotes extinction memory retrieval PMCID:    Pubmed No.:28888982 Fluid shear stress inhibits TNF-α-induced osteoblast apoptosis via ERK5 signaling pathway PMCID:    Pubmed No.:26325467 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition PMCID:    Pubmed No.:26316083 Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells PMCID:    Pubmed No.:26035796 Nicotine stimulates expression of proteins implicated in peripheral and central sensitization PMCID:    Pubmed No.:25637801 Long Non-Coding RNA MDFIC-7 Promotes Chordoma Progression Through Modulating the miR-525-5p/ARF6 Axis PMCID:    Pubmed No.:34621682 Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma PMCID:    Pubmed No.:31209283 Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways PMCID:    Pubmed No.:29650947 Taeumjowi-tang, a Traditional Korean Sasang Remedy, Improves Obesity-Atopic Dermatitis Comorbidity by Regulating Hypoxia-Inducible Factor 1 Alpha PMCID:    Pubmed No.:31920651 Anti-neuroinflammatory Effect of Short-Chain Fatty Acid Acetate against Alzheimer’s Disease via Upregulating GPR41 and Inhibiting ERK/JNK/NF-κB PMCID:    Pubmed No.:32583667 Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma PMCID:    Pubmed No.:32157550 Sp2 promotes invasion and metastasis of hepatocellular carcinoma by targeting TRIB3 protein PMCID:    Pubmed No.:32160655 Estrogen promotes the metastasis of non‑small cell lung cancer via estrogen receptor β by upregulation of Toll‑like receptor 4 and activation of the myd88/NF‑κB/MMP2 pathway PMCID:    Pubmed No.:32364243 Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways PMCID:    Pubmed No.:33565424 Sub‐chronic administration of benzo[a]pyrene disrupts hippocampal long‐term potentiation via inhibiting CaMK II/PKC/PKA‐ERK‐CREB signaling in rats PMCID:    Pubmed No.:32255272 TRIB2 knockdown as a regulator of chemotherapy resistance and proliferation via the ERK/STAT3 signaling pathway in human chronic myelogenous leukemia K562/ADM cells PMCID:    Pubmed No.:29436678 The combined usage of Matrine and Osthole inhibited endoplasmic reticulum apoptosis induced by PCV2 PMCID:    Pubmed No.:33046006 Let-7b regulates the adriamycin resistance of chronic myelogenous leukemia by targeting AURKB in K562/ADM cells PMCID:    Pubmed No.:32856506 Activation of RAW264.7 macrophage by Exopolysaccharide from Aphanothece halaphytica (EPSAH) and the underlying mechanisms PMCID:    Pubmed No.:32083746 4‐Sulfonyloxy/alkoxy benzoxazolone derivatives with high anti‐inflammatory activities: Synthesis, biological evaluation, and action mechanism via p38/ERK‐NF‐κB/iNOS pathway PMCID:    Pubmed No.:32915501 Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer PMCID:    Pubmed No.:32851058 -Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells PMCID:    Pubmed No.:30363706 Phosphorylated Hsp27 prevents LPS‐induced excessive inflammation in THP‐1 cells via suppressing ROS‐mediated upregulation of CBP PMCID:    Pubmed No.:31483551 PKG II inhibits PDGF‐BB triggered biological activities by phosphorylating PDGFRβ in gastric cancer cells PMCID:    Pubmed No.:29935031 L-Theanine Down-Regulates the JAK/STAT3 Pathway to Attenuate the Proliferation and Migration of Vascular Smooth Muscle Cells Induced by Angiotensin II PMCID:    Pubmed No.:30381668 EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer PMCID:    Pubmed No.:29620175 Zurampic Protects Pancreatic β-Cells from High Uric Acid Induced-Damage by Inhibiting URAT1 and Inactivating the ROS/AMPK/ERK Pathways PMCID:    Pubmed No.:29843128 Fuzhuan Brick Tea Boosts Melanogenesis and Prevents Hair Graying through Reduction of Oxidative Stress via NRF2-HO-1 Signaling PMCID:    Pubmed No.:35326249 ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy PMCID:    Pubmed No.:37031357 IFN-γ enhances the therapeutic efficacy of MSCs-derived exosome via miR-126-3p in diabetic wound healing by targeting SPRED1 PMCID:    Pubmed No.:37646268