Product Name :
Mouse anti human collagen IV a1 Chain Background :
Alport's syndrome, an inherited disease, shows absence or reduction of the a5 chain in the glomerular, tubular and bowman's capsular basement membranes. Normal human kidney has a1 (TV) to a6 (IV) chains in the renal basement membrance. Product :
Appearance:Solution,Monoclonal antibodies were purified by affinity chromatography.0.02% ProClin 300 is added for preservation. Storage&Stability :
Store at 4°C. Specificity :
4E5E2-1 (mouse lgG1/kappa) is specific to NC1 domain of a3 (IV). Immunogen :
Synthetic peptides NC1 domain of type lV collagen. Conjugate :
Unconjugated Modification :
Unmodification

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  FITC fluorescence a1 chain is observed in the GBM and TBM.

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

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Price/Size :

USD 368/1mg/vial

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Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

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Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

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Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

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Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

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Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

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