Blood-brain barrier dysfunction induced by silica NPs in vitro and in vivo: Involvement of oxidative stress and Rho-kinase/JNK signaling pathways PMCID:    Pubmed No.:28081460 TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways PMCID:    Pubmed No.:27669982 Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer PMCID:    Pubmed No.:26649143 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation PMCID:    Pubmed No.:28076833 Isorhapontigenin induced cell growth inhibition and apoptosis by targeting EGFR-related pathways in prostate cancer PMCID:    Pubmed No.:28422286 Osteoinduction and long-term osseointegration promoted by combined effects of nitrogen and manganese elements in high nitrogen nickel-free stainless steel PMCID:    Pubmed No.:32262962 Electromagnetic-pulse-induced activation of p38 MAPK pathway and disruption of blood–retinal barrier PMCID:    Pubmed No.:23570913 Acquisition of epithelial-mesenchymal transition phenotype in the tamoxifen-resistant breast cancer cell: a new role for G protein-coupled estrogen receptor in mediating tamoxifen resistance through cancer-associated fibroblast-derived fibronectin and β2- PMCID:    Pubmed No.:25990368 Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma PMCID:    Pubmed No.:29075359 Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro PMCID:    Pubmed No.:28413317 Persistent Transmissible Gastroenteritis Virus Infection Enhances Enterotoxigenic Escherichia coli K88 Adhesion by Promoting Epithelial-Mesenchymal Transition in Intestinal Epithelial Cells | Journal of Virology PMCID:    Pubmed No.:28794036 Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons PMCID:    Pubmed No.:26363976 Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell PMCID:    Pubmed No.:28280522 SP1-mediated microRNA-520d-5p suppresses tumor growth and metastasis in colorectal cancer by targeting CTHRC4 PMCID:    Pubmed No.:26101709 17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway PMCID:    Pubmed No.:25403930 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function PMCID:    Pubmed No.:26349994 Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway PMCID:    Pubmed No.:27799770 Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer PMCID:    Pubmed No.:25928008 IGF-1/IGF-1R/ hsa-let-7c axis regulates the committed differentiation of stem cells from apical papilla PMCID:    Pubmed No.:27833148 Mechanisms of Gefitinib-mediated reversal of tamoxifen resistance in MCF-7 breast cancer cells by inducing ERα re-expression PMCID:    Pubmed No.:25644501 The expression and function of miR-424 in infantile skin hemangioma and its mechanism PMCID:    Pubmed No.:28928430 Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways PMCID:    Pubmed No.:29116196 The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow PMCID:    Pubmed No.:29118325 Effects of dietary methionine on breast muscle growth, myogenic gene expression and IGF-I signaling in fast- and slow-growing broilers PMCID:    Pubmed No.:28507342 IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway PMCID:    Pubmed No.:26549519 TNF‐α downregulates CIDEC via MEK/ERK pathway in human adipocytes PMCID:    Pubmed No.:27062372 DGAEE, a newly synthesized derivative of glycyrrhetinic acid, potently attenuates mouse septic shock via its main metabolite DGA in an IL-10-dependent manner PMCID:    Pubmed No.:26456500 Protective effect of butyrate against ethanol-induced gastric ulcers in mice by promoting the anti-inflammatory, anti-oxidant and mucosal defense mechanisms PMCID:    Pubmed No.:26604089 Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways PMCID:    Pubmed No.:26503828 Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF‐9/MAPK/Smad pathway PMCID:    Pubmed No.:28346732 PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-κB-dependent pathway PMCID:    Pubmed No.:25876056 Outer Membrane Protein 26 of Brucella Activates Mitogen-Activated Protein Kinase Signal Pathway in Human Trophoblast Cells PMCID:    Pubmed No.:29326948 Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells PMCID:    Pubmed No.:26708214 Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways PMCID:    Pubmed No.:27060196 Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways PMCID:    Pubmed No.:27261558 Chrysin alleviates allergic inflammation and airway remodeling in a murine model of chronic asthma PMCID:    Pubmed No.:26780233 Biochanin A Protects Against Lipopolysaccharide-Induced Damage of Dopaminergic Neurons Both In Vivo and In Vitro via Inhibition of Microglial Activation PMCID:    Pubmed No.:27417698 Naringin prevents carbon tetrachloride-induced acute liver injury in mice PMCID:    Pubmed No.:36559593 Potent effects of dioscin against thioacetamide-induced liver fibrosis through attenuating oxidative stress in turn inhibiting inflammation, TGF-β/Smad and MAPK signaling pathways PMCID:    Pubmed No.:28070230 Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion PMCID:    Pubmed No.:26849940 Daphnetin reduces endotoxin lethality in mice and decreases LPS-induced inflammation in Raw264.7 cells via suppressing JAK/STATs activation and ROS production PMCID:    Pubmed No.:28409189 Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer PMCID:    Pubmed No.:25241857 Tetramethylpyrazine induces SH-SY5Y cell differentiation toward the neuronal phenotype through activation of the PI3K/Akt/Sp1/TopoIIβ pathway PMCID:    Pubmed No.:26518113 Disrupting nNOS-PSD-95 coupling in the hippocampal dentate gyrus promotes extinction memory retrieval PMCID:    Pubmed No.:28888982 Fluid shear stress inhibits TNF-α-induced osteoblast apoptosis via ERK5 signaling pathway PMCID:    Pubmed No.:26325467 Annosquacin B induces mitochondrial apoptosis in multidrug resistant human breast cancer cell line MCF-7/ADR through selectively modulating MAPKs pathways PMCID:    Pubmed No.:27450387 Knockdown of Astrocyte Elevated Gene-1 Inhibits Activation of Hepatic Stellate Cells PMCID:    Pubmed No.:26879903 Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro PMCID:    Pubmed No.:26104582 Increased Thymic Cell Turnover under Boron Stress May Bypass TLR3/4 Pathway in African Ostrich PMCID:    Pubmed No.:26053067 MSTN, mTOR and FoxO4 Are Involved in the Enhancement of Breast Muscle Growth by Methionine in Broilers with Lower Hatching Weight PMCID:    Pubmed No.:25437444 Evidence for a role of GPRC6A in prostate cancer metastasis based on case-control and in vitro analyses. PMCID:    Pubmed No.:27338047 M3 receptor is involved in the effect of penehyclidine hydrochloride reduced endothelial injury in LPS-stimulated human pulmonary microvascular endothelial cell PMCID:    Pubmed No.:29158153 Heparin-Binding Epidermal Growth Factor-Like Growth Factor Enhances Aquaporin 3 Expression and Function During Mouse Embryo Implantation PMCID:    Pubmed No.:27436370 Heparin-Binding Epidermal Growth Factor-Like Growth Factor Enhances Aquaporin 3 Expression and Function During Mouse Embryo Implantation PMCID:    Pubmed No.:27436370 MicroRNA-9 regulates cardiac fibrosis by targeting PDGFR-β in rats PMCID:    Pubmed No.:26896308 Effects of selenium on the proliferation, apoptosis and testosterone production of sheep Leydig cells in vitro PMCID:    Pubmed No.:28257863 Reduced β‑2‑glycoprotein І inhibits hypoxia‑induced retinal angiogenesis in neonatal mice through the vascular endothelial growth factor pathway PMCID:    Pubmed No.:25374014 The Inhibitory Effect of Eplerenone on Cell Proliferation in the Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction PMCID:    Pubmed No.:28402979 Insulin-like growth factor 1 promotes the proliferation and committed differentiation of human dental pulp stem cells through MAPK pathways PMCID:    Pubmed No.:27573439 Local renin-angiotensin system regulates hypoxia-induced vascular endothelial growth factor synthesis in mesenchymal stem cells PMCID:    Pubmed No.:26045756 Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3 PMCID:    Pubmed No.:27517321 N-cadherin promotes thyroid tumorigenesis through modulating major signaling pathways PMCID:    Pubmed No.:28042956 N-cadherin promotes thyroid tumorigenesis through modulating major signaling pathways PMCID:    Pubmed No.:28042956 Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing PMCID:    Pubmed No.:28422736 4,4′-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner PMCID:    Pubmed No.:27276712 STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation PMCID:    Pubmed No.:26919241 SiRNA Directed Against Annexin II Receptor Inhibits Angiogenesis via Suppressing MMP2 and MMP9 Expression PMCID:    Pubmed No.:25633185 Afatinib reverses multidrug resistance in ovarian cancer via dually inhibiting ATP binding cassette subfamily B member 1 PMCID:    Pubmed No.:26317651 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition PMCID:    Pubmed No.:26316083 Interleukin-6 suppression reduces tumour self-seeding by circulating tumour cells in a human osteosarcoma nude mouse model PMCID:    Pubmed No.:26623559 Inhibition of IL-8-mediated endothelial adhesion, VSMCs proliferation and migration by siRNA-TMEM98 suggests TMEM98's emerging role in atherosclerosis PMCID:    Pubmed No.:29152140 Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells PMCID:    Pubmed No.:26035796 Ruscogenin suppresses mouse neutrophil activation: Involvement of protein kinase A pathway PMCID:    Pubmed No.:26134424 Role of the MAPK pathway in the observed bystander effect in lymphocytes co-cultured with macrophages irradiated with γ-rays or carbon ions PMCID:    Pubmed No.:25748424 GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis PMCID:    Pubmed No.:28902352 The antimetastatic effect and underlying mechanisms of thioredoxin reductase inhibitor ethaselen PMCID:    Pubmed No.:30496814 MRP8/14 mediates macrophage efferocytosis through RAGE and Gas6/MFG‐E8, and induces polarization via TLR4‐dependent pathway PMCID:    Pubmed No.:33128793 Tropomodulin1 Expression Increases Upon Maturation in Dendritic Cells and Promotes Their Maturation and Immune Functions PMCID:    Pubmed No.:33552047 Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways PMCID:    Pubmed No.:29650947 Anti-neuroinflammatory Effect of Short-Chain Fatty Acid Acetate against Alzheimer’s Disease via Upregulating GPR41 and Inhibiting ERK/JNK/NF-κB PMCID:    Pubmed No.:32583667 Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma PMCID:    Pubmed No.:32157550 A novel biscoumarin derivative dephosphorylates ERK and alleviates apoptosis induced by mitochondrial oxidative damage in ischemic stroke mice PMCID:    Pubmed No.:33141045 A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial Defect in a Rat Model PMCID:    Pubmed No.:30950322 Traditional Chinese Medicine CFF‐1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR‐related pathways in prostate cancer PMCID:    Pubmed No.:29533017 Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways PMCID:    Pubmed No.:33565424 Sub‐chronic administration of benzo[a]pyrene disrupts hippocampal long‐term potentiation via inhibiting CaMK II/PKC/PKA‐ERK‐CREB signaling in rats PMCID:    Pubmed No.:32255272 Let-7b regulates the adriamycin resistance of chronic myelogenous leukemia by targeting AURKB in K562/ADM cells PMCID:    Pubmed No.:32856506 Activation of RAW264.7 macrophage by Exopolysaccharide from Aphanothece halaphytica (EPSAH) and the underlying mechanisms PMCID:    Pubmed No.:32083746 4‐Sulfonyloxy/alkoxy benzoxazolone derivatives with high anti‐inflammatory activities: Synthesis, biological evaluation, and action mechanism via p38/ERK‐NF‐κB/iNOS pathway PMCID:    Pubmed No.:32915501 Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer PMCID:    Pubmed No.:32851058 -Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells PMCID:    Pubmed No.:30363706 Cross regulation of signaling pathways in gastrointestinal stromal tumor PMCID:    Pubmed No.:30405821 L-Theanine Down-Regulates the JAK/STAT3 Pathway to Attenuate the Proliferation and Migration of Vascular Smooth Muscle Cells Induced by Angiotensin II PMCID:    Pubmed No.:30381668 EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer PMCID:    Pubmed No.:29620175 Zurampic Protects Pancreatic β-Cells from High Uric Acid Induced-Damage by Inhibiting URAT1 and Inactivating the ROS/AMPK/ERK Pathways PMCID:    Pubmed No.:29843128