ATG4C monoclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
ATG4C monoclonal antibody Background :
Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUT_x005Flike 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase),APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee,canine, bovine, mouse, rat, chicken and zebrafish. Atg4C is highly expressedin skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Functioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP.Atg4C is also inhibited by N-ethylmaleimide. Product :
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Recognizes endogenous levels of ATG4C protein. Immunogen :
Recombinant fusion protein of human ATG4C. The exact sequence is proprietary. Conjugate :
Unconjugated Modification :
Unmodification
ATG4C monoclonal antibody Background :
Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUT_x005Flike 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase),APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee,canine, bovine, mouse, rat, chicken and zebrafish. Atg4C is highly expressedin skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Functioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP.Atg4C is also inhibited by N-ethylmaleimide. Product :
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Recognizes endogenous levels of ATG4C protein. Immunogen :
Recombinant fusion protein of human ATG4C. The exact sequence is proprietary. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot analysis of ATG4C expression in mouse heart (A) whole cell lysates.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.