GMFG monoclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
GMFG monoclonal antibody Background :
GMF-γ (glia maturation factor, γ), also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger Actin-binding protein ADF family. GMF-γ is expressed predominantly in lung, heart and placenta.GMF-γ is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-γ is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-γ expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of Actin-based cellular functions, GMF-γ may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-γ is primarily found in proliferative and differentiative organs. Product :
Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Recognizes endogenous levels of GMFG protein. Immunogen :
Recombinant fusion protein of human GMFG. The exact sequence is proprietary. Conjugate :
Unconjugated Modification :
Unmodification
GMFG monoclonal antibody Background :
GMF-γ (glia maturation factor, γ), also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger Actin-binding protein ADF family. GMF-γ is expressed predominantly in lung, heart and placenta.GMF-γ is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-γ is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-γ expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of Actin-based cellular functions, GMF-γ may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-γ is primarily found in proliferative and differentiative organs. Product :
Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Recognizes endogenous levels of GMFG protein. Immunogen :
Recombinant fusion protein of human GMFG. The exact sequence is proprietary. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot analysis of GMFG expression in Jurkat (A) whole cell lysates.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.