IGF2BP3 monoclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
IGF2BP3 monoclonal antibody Background :
Insulin-like growth factor-II mRNA-binding proteins (IMPs) belong to a family of zipcode-binding proteins. Three members of this family, IMP1, IMP2, and IMP3, have been identified. They contain two RNA recognition motifs, four K homology domains, and were found to function in mRNA localization, turnover, and translation control. Research studies have implicated these proteins in a variety of physiological and pathological processes, such as growth and development, testicular neoplasia, and melanocytic neoplasia. IMP3 is an oncofetal protein expressed in developing tissues as well as in many tumor types. Expression of IMP3 is a marker for poor prognosis and metastasis in a variety of cancers. Product :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Recognizes endogenous levels of IGF2BP3 protein. Immunogen :
Purified recombinant human IMP3 protein fragments expressed in E.coli. Conjugate :
Unconjugated Modification :
Unmodification
IGF2BP3 monoclonal antibody Background :
Insulin-like growth factor-II mRNA-binding proteins (IMPs) belong to a family of zipcode-binding proteins. Three members of this family, IMP1, IMP2, and IMP3, have been identified. They contain two RNA recognition motifs, four K homology domains, and were found to function in mRNA localization, turnover, and translation control. Research studies have implicated these proteins in a variety of physiological and pathological processes, such as growth and development, testicular neoplasia, and melanocytic neoplasia. IMP3 is an oncofetal protein expressed in developing tissues as well as in many tumor types. Expression of IMP3 is a marker for poor prognosis and metastasis in a variety of cancers. Product :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Recognizes endogenous levels of IGF2BP3 protein. Immunogen :
Purified recombinant human IMP3 protein fragments expressed in E.coli. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot analysis of IGF2BP3 expression in MCF7 (A), SKVO3 (B), NTERA2 (C), Jurkat (D), Hela (E), K562 (F) whole cell lysates.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.