Product Name :
Heartland bandavirus Nucleocapsid Protein polyclonal antibody Background :
Heartland virus (HRTV) is a recently described tick-borne phlebovirus. Phleboviruses are single-stranded RNA viruses in the family Bunyaviridae. The original two cases of HRTV disease were initially reported in adult males from Missouri. Both case-patients presented with a non-specific febrile illness with leukopenia and thrombocytopenia and history of tick exposure. They were initially diagnosed with ehrlichiosis for which they received doxycycline. The case-patients required hospitalization for approximately 11 days before being discharged to home where they eventually recovered. Subsequent field work identified the virus in Ambylommaamericanum ticks collected on one of the original patient’s farms and at a nearby site . Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Heartland bandavirus Nucleocapsid Protein polyclonal antibody detects endogenous levels of HRTV-NP protein. Immunogen :
Recombinant protein of HRTV-NP. Conjugate :
Unconjugated Modification :
Unmodification
Heartland bandavirus Nucleocapsid Protein polyclonal antibody Background :
Heartland virus (HRTV) is a recently described tick-borne phlebovirus. Phleboviruses are single-stranded RNA viruses in the family Bunyaviridae. The original two cases of HRTV disease were initially reported in adult males from Missouri. Both case-patients presented with a non-specific febrile illness with leukopenia and thrombocytopenia and history of tick exposure. They were initially diagnosed with ehrlichiosis for which they received doxycycline. The case-patients required hospitalization for approximately 11 days before being discharged to home where they eventually recovered. Subsequent field work identified the virus in Ambylommaamericanum ticks collected on one of the original patient’s farms and at a nearby site . Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Heartland bandavirus Nucleocapsid Protein polyclonal antibody detects endogenous levels of HRTV-NP protein. Immunogen :
Recombinant protein of HRTV-NP. Conjugate :
Unconjugated Modification :
Unmodification
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.