Contact us : info@bioworlde.com
Home > Product > Primary Antibodies
Semaphorin 4D monoclonal antibody MB11579
  • Immunocytochemistry analysis of Semaphorin 4D in Jurkat using Semaphorin 4D antibody,and DAPI.
  • Western blot analysis of Semaphorin 4D/CD100 in Jurkat lysates using Semaphorin 4D/CD100 antibody.
Product NameSemaphorin 4D monoclonal antibody
Catalog No.MB11579
Swiss-ProtQ92854
Host Rabbit
ReactivityHuman
ApplicationsWB,ICC/IF
Application_allWB: 1/500-1/1000 IF: 1/50-1/200
BiowMWCalculated MW: 96 kDa; Observed MW: 120 kDa
Alternative NameCD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G
Purification&PurityAffinity Purified
ConjugateUnconjugated
ModificationUnmodified
Browse similar products>>
Size Price
50ul $258
100ul $398
Add to cart My orders
Product Name :
Semaphorin 4D monoclonal antibody
Background :
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Product :
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
IgG
Immunogen :
A synthetic peptide of human Semaphorin 4D
Conjugate :
Unconjugated
Modification :
Unmodified
  • Immunocytochemistry analysis of Semaphorin 4D in Jurkat using Semaphorin 4D antibody,and DAPI.
  • Western blot analysis of Semaphorin 4D/CD100 in Jurkat lysates using Semaphorin 4D/CD100 antibody.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
COPYRIGHT © 2015-2018 Bioworld Technology, Inc. All rights reserved POLYCLONAL AND MONOCLONAL ANTIBODY CENTER